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TMPRSS2 and BMP10
Data Source:
BioGRID
(two hybrid)
TMPRSS2
BMP10
Description
transmembrane serine protease 2
bone morphogenetic protein 10
Image
No pdb structure
GO Annotations
Cellular Component
Nucleoplasm
Plasma Membrane
Integral Component Of Plasma Membrane
Extracellular Exosome
Extracellular Region
Extracellular Space
Cytoplasm
Cell Surface
Z Disc
Molecular Function
Serine-type Endopeptidase Activity
Scavenger Receptor Activity
Protein Binding
Serine-type Peptidase Activity
Cytokine Activity
Hormone Activity
Protein Binding
Growth Factor Activity
Telethonin Binding
Receptor Serine/threonine Kinase Binding
Biological Process
Proteolysis
Endocytosis
Protein Autoprocessing
Positive Regulation Of Viral Entry Into Host Cell
Kidney Development
Cell Adhesion
Adult Heart Development
Negative Regulation Of Endothelial Cell Migration
Positive Regulation Of Cardiac Muscle Hypertrophy
Negative Regulation Of Cardiac Muscle Hypertrophy
Positive Regulation Of Pathway-restricted SMAD Protein Phosphorylation
Negative Regulation Of Cell Growth
Negative Regulation Of Cell Migration
BMP Signaling Pathway
Activin Receptor Signaling Pathway
Sarcomere Organization
Positive Regulation Of Transcription, DNA-templated
Atrial Cardiac Muscle Tissue Morphogenesis
Ventricular Cardiac Muscle Tissue Morphogenesis
Ventricular Cardiac Muscle Cell Development
Regulation Of Cardiac Muscle Contraction
Cardiac Muscle Cell Proliferation
Positive Regulation Of Cardiac Muscle Cell Proliferation
Positive Regulation Of Sarcomere Organization
Heart Trabecula Formation
Pathway-restricted SMAD Protein Phosphorylation
SMAD Protein Signal Transduction
Positive Regulation Of Cartilage Development
Regulation Of Cardiac Muscle Hypertrophy In Response To Stress
Positive Regulation Of Cell Proliferation Involved In Heart Morphogenesis
Pathways
Attachment and Entry
Attachment and Entry
Attachment and Entry
Signaling by BMP
Molecules associated with elastic fibres
Drugs
Camostat
Diseases
Prostate cancer
GWAS
Amyotrophic lateral sclerosis (sporadic) (
24529757
)
Prostate cancer (
25217961
)
Interacting Genes
59 interacting genes:
ADIPOQ
ANKRD46
AQP1
BMP10
BNIP2
BNIP3
BRICD5
C1QL4
C2CD2L
C3orf52
CFHR5
CLEC7A
CLK1
CLN6
CMTM7
CNIH2
CNIH3
CTXN3
CXCL9
CYBC1
DEFB103A
DEFB103B
EDDM3B
ERG28
FAM3C
FAXDC2
IGFBP5
MOSPD3
NINJ2
PGAP2
PLLP
PLN
PLP1
PLP2
PTCH1
PTTG1IP
SCD
SEC22A
SELENOK
SFTPC
SLC35A1
SMIM1
STX7
STX8
TMEM11
TMEM120B
TMEM128
TMEM218
TMEM222
TMEM229B
TMEM243
TMEM60
TMEM79
TMEM86A
TMEM86B
TNF
UPK2
VAMP5
ZFPL1
59 interacting genes:
ACVR2A
ACVR2B
APOA5
AQP6
ARL13B
BIK
BMPR2
BSCL2
BSND
CCDC70
CD33
CISD2
CLDN7
COQ9
CREB3L1
DEXI
EBP
ERP29
FAM209A
FCGR1A
FCRL4
FFAR2
FKBP7
FNDC9
GGT6
GJB1
GPR152
GPX8
IL3RA
JAGN1
KIR2DL3
KIR3DL1
KLRC1
LRRC25
LRRC4C
MGST3
MRPS18B
MS4A3
MTIF3
PLPP4
REEP4
SERINC3
SIT1
SLC10A1
SLC10A6
SLC35C2
SLC38A1
SLC4A1
SPAG4
TCTA
TMEM14B
TMEM31
TMEM45B
TMEM86B
TMPRSS2
TNFSF14
TNFSF8
TSPAN31
VSIR
Entrez ID
7113
27302
HPRD ID
03637
09788
Ensembl ID
ENSG00000184012
ENSG00000163217
Uniprot IDs
O15393
O95393
PDB IDs
6SF1
6SF3
Enriched GO Terms of Interacting Partners
?
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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