TMPRSS2 and C2CD2L

Data Source:
BioGRID (two hybrid)

		TMPRSS2	C2CD2L
Description		transmembrane serine protease 2	C2CD2 like
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Plasma Membrane Integral Component Of Plasma Membrane Extracellular Exosome	Endoplasmic Reticulum Membrane Integral Component Of Membrane Cortical Endoplasmic Reticulum Cytoplasmic Side Of Apical Plasma Membrane Endoplasmic Reticulum-plasma Membrane Contact Site
	Molecular Function	Serine-type Endopeptidase Activity Scavenger Receptor Activity Protein Binding Serine-type Peptidase Activity	Protein Binding Phosphatidylinositol Transfer Activity Phosphatidylinositol Binding Insulin Binding
	Biological Process	Proteolysis Endocytosis Protein Autoprocessing Positive Regulation Of Viral Entry Into Host Cell	Phospholipid Transport Positive Regulation Of Insulin Secretion Involved In Cellular Response To Glucose Stimulus Intermembrane Lipid Transfer
Pathways		Attachment and Entry Attachment and Entry Attachment and Entry
Drugs		Camostat
Diseases		Prostate cancer
GWAS		Amyotrophic lateral sclerosis (sporadic) ( 24529757) Prostate cancer ( 25217961)	Heel bone mineral density ( 30598549)
Interacting Genes		59 interacting genes: ADIPOQ ANKRD46 AQP1 BMP10 BNIP2 BNIP3 BRICD5 C1QL4 C2CD2L C3orf52 CFHR5 CLEC7A CLK1 CLN6 CMTM7 CNIH2 CNIH3 CTXN3 CXCL9 CYBC1 DEFB103A DEFB103B EDDM3B ERG28 FAM3C FAXDC2 IGFBP5 MOSPD3 NINJ2 PGAP2 PLLP PLN PLP1 PLP2 PTCH1 PTTG1IP SCD SEC22A SELENOK SFTPC SLC35A1 SMIM1 STX7 STX8 TMEM11 TMEM120B TMEM128 TMEM218 TMEM222 TMEM229B TMEM243 TMEM60 TMEM79 TMEM86A TMEM86B TNF UPK2 VAMP5 ZFPL1	32 interacting genes: AQP6 ARL13B CD79A CHODL CISD2 CLRN1 CPEB2 CXCR3 EBP ELOVL5 EPB41 FCER1G GJA8 GJB1 HIBADH IL3RA MFSD5 MUC1 OPRM1 PDZK1IP1 REEP2 REEP4 SDCBP SLC10A6 SLC18A1 TMEM14B TMEM179B TMEM31 TMEM86B TMEM9 TMPRSS2 TMX2
Entrez ID		7113	9854
HPRD ID		03637	15533
Ensembl ID		ENSG00000184012	ENSG00000172375
Uniprot IDs		O15393	O14523
PDB IDs			5TOD
Enriched GO Terms of Interacting Partners?
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