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TMEM218 and NPFFR2
Data Source:
BioGRID
(two hybrid)
TMEM218
NPFFR2
Description
transmembrane protein 218
neuropeptide FF receptor 2
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Cilium
Integral Component Of Membrane
Plasma Membrane
Integral Component Of Plasma Membrane
Actin Cytoskeleton
Molecular Function
Protein Binding
G Protein-coupled Receptor Activity
Neuropeptide Receptor Activity
Opioid Receptor Binding
Peptide Binding
Biological Process
G Protein-coupled Receptor Signaling Pathway
Neuropeptide Signaling Pathway
Detection Of Abiotic Stimulus
Regulation Of MAPK Cascade
Regulation Of Adenylate Cyclase Activity
Regulation Of CAMP-dependent Protein Kinase Activity
Pathways
Orexin and neuropeptides FF and QRFP bind to their respective receptors
G alpha (q) signalling events
Drugs
Diseases
GWAS
Breast cancer (survival) (
25890600
)
Familial lung adenocarcinoma (
29924316
)
Interacting Genes
72 interacting genes:
APH1A
AQP2
AQP6
ARL13B
ASZ1
ATP6V0E1
BSCL2
CD300A
CD53
CD79A
CLDN2
CLEC10A
CLEC17A
CPLX4
CREB3L1
CTLA4
DAGLA
EBP
ELOVL2
ELOVL4
EMP1
ERGIC3
FAM209A
FCER1G
FRMD3
GDAP1
GJB1
GJB4
GJB6
GPR152
GPR61
GPX8
IFNGR2
KCNJ6
KCNK5
KIR2DL3
LDLRAD1
LHFPL5
LMNA
LSMEM2
MFF
MS4A3
MTIF3
NPFFR2
PCNA
PDCD1LG2
PIK3IP1
PLEKHO1
PSCA
RETREG3
SAR1A
SDC3
SLC10A4
SLC10A6
SLC18A1
SMIM3
SSMEM1
TM4SF18
TMED8
TMEM106C
TMEM182
TMEM207
TMEM234
TMEM31
TMEM45B
TMEM52B
TMEM88
TMPRSS2
TRHR
TSPAN12
TSPAN18
VSIR
6 interacting genes:
FKBP7
HCRT
NPFF
NPY
TMEM218
TRARG1
Entrez ID
219854
10886
HPRD ID
19054
16244
Ensembl ID
ENSG00000150433
ENSG00000056291
Uniprot IDs
A2RU14
A0PJM9
Q9Y5X5
PDB IDs
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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