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TMEM218 and TSPAN12
Data Source:
BioGRID
(two hybrid)
TMEM218
TSPAN12
Description
transmembrane protein 218
tetraspanin 12
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Cilium
Integral Component Of Membrane
Integral Component Of Plasma Membrane
Membrane
Integral Component Of Membrane
Molecular Function
Protein Binding
Protein Binding
Wnt-activated Receptor Activity
Biological Process
Angiogenesis
Cell Surface Receptor Signaling Pathway
Retina Layer Formation
Wnt Signaling Pathway
Regulation Of Angiogenesis
Regulation Of Vascular Endothelial Growth Factor Signaling Pathway
Pathways
Drugs
Diseases
Familial exudative vitreoretinopathy (FEVR), including: Exudative vitreoretinopathy 1 (EVR1); Exudative vitreoretinopathy2, X-linked (EVR2); Exudative vitreoretinopathy 4 (EVR4); Exudative vitreoretinopathy 5 (EVR5); Norrie disease (ND)
GWAS
Breast cancer (survival) (
25890600
)
Familial lung adenocarcinoma (
29924316
)
Bitter alcoholic beverage consumption (
31046077
)
Heel bone mineral density (
30598549
)
Interacting Genes
72 interacting genes:
APH1A
AQP2
AQP6
ARL13B
ASZ1
ATP6V0E1
BSCL2
CD300A
CD53
CD79A
CLDN2
CLEC10A
CLEC17A
CPLX4
CREB3L1
CTLA4
DAGLA
EBP
ELOVL2
ELOVL4
EMP1
ERGIC3
FAM209A
FCER1G
FRMD3
GDAP1
GJB1
GJB4
GJB6
GPR152
GPR61
GPX8
IFNGR2
KCNJ6
KCNK5
KIR2DL3
LDLRAD1
LHFPL5
LMNA
LSMEM2
MFF
MS4A3
MTIF3
NPFFR2
PCNA
PDCD1LG2
PIK3IP1
PLEKHO1
PSCA
RETREG3
SAR1A
SDC3
SLC10A4
SLC10A6
SLC18A1
SMIM3
SSMEM1
TM4SF18
TMED8
TMEM106C
TMEM182
TMEM207
TMEM234
TMEM31
TMEM45B
TMEM52B
TMEM88
TMPRSS2
TRHR
TSPAN12
TSPAN18
VSIR
21 interacting genes:
CDS2
CTXN3
CXCL16
CYBC1
EMP3
GPR25
GPR37L1
IGFBP5
MARCHF2
MGST3
NINJ2
PMP22
RFT1
RNF152
STX8
TEX264
TFCP2
TMEM140
TMEM147
TMEM182
TMEM218
Entrez ID
219854
23554
HPRD ID
19054
15509
Ensembl ID
ENSG00000150433
ENSG00000106025
Uniprot IDs
A2RU14
A0A024R740
O95859
PDB IDs
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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