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TMPRSS2 and CXCL9
Data Source:
BioGRID
(two hybrid)
TMPRSS2
CXCL9
Description
transmembrane serine protease 2
C-X-C motif chemokine ligand 9
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Nucleoplasm
Plasma Membrane
Integral Component Of Plasma Membrane
Extracellular Exosome
Extracellular Region
Extracellular Space
External Side Of Plasma Membrane
Molecular Function
Serine-type Endopeptidase Activity
Scavenger Receptor Activity
Protein Binding
Serine-type Peptidase Activity
Cytokine Activity
Protein Binding
Chemokine Activity
CXCR Chemokine Receptor Binding
CXCR3 Chemokine Receptor Binding
Biological Process
Proteolysis
Endocytosis
Protein Autoprocessing
Positive Regulation Of Viral Entry Into Host Cell
Chemotaxis
Defense Response
Inflammatory Response
Cellular Defense Response
Signal Transduction
G Protein-coupled Receptor Signaling Pathway
Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway
Cell-cell Signaling
Neutrophil Chemotaxis
Regulation Of Cell Population Proliferation
Positive Regulation Of Myoblast Differentiation
Positive Regulation Of Release Of Sequestered Calcium Ion Into Cytosol
Defense Response To Virus
Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide
Chemokine-mediated Signaling Pathway
Cellular Response To Lipopolysaccharide
Positive Regulation Of Myoblast Fusion
Pathways
Attachment and Entry
Attachment and Entry
Attachment and Entry
Chemokine receptors bind chemokines
G alpha (i) signalling events
Drugs
Camostat
Diseases
Prostate cancer
GWAS
Amyotrophic lateral sclerosis (sporadic) (
24529757
)
Prostate cancer (
25217961
)
Blood protein levels (
28240269
)
Hippocampal volume (
29274321
)
Neonatal cytokine/chemokine levels (fetal genetic effect) (
30134952
)
Interacting Genes
59 interacting genes:
ADIPOQ
ANKRD46
AQP1
BMP10
BNIP2
BNIP3
BRICD5
C1QL4
C2CD2L
C3orf52
CFHR5
CLEC7A
CLK1
CLN6
CMTM7
CNIH2
CNIH3
CTXN3
CXCL9
CYBC1
DEFB103A
DEFB103B
EDDM3B
ERG28
FAM3C
FAXDC2
IGFBP5
MOSPD3
NINJ2
PGAP2
PLLP
PLN
PLP1
PLP2
PTCH1
PTTG1IP
SCD
SEC22A
SELENOK
SFTPC
SLC35A1
SMIM1
STX7
STX8
TMEM11
TMEM120B
TMEM128
TMEM218
TMEM222
TMEM229B
TMEM243
TMEM60
TMEM79
TMEM86A
TMEM86B
TNF
UPK2
VAMP5
ZFPL1
76 interacting genes:
AMIGO1
AQP6
ATP1B4
BMF
BSCL2
BTNL9
C16orf92
CCL11
CCL13
CCL2
CCL21
CCL26
CCL28
CCL5
CCR3
CD33
CHODL
CLDN2
CLDN5
CLDN7
CLEC17A
CLEC2D
CLEC4E
CLEC7A
CXCL10
CXCL11
CXCL12
CXCL14
CXCL17
CXCL2
CXCR3
DPP4
EPGN
EREG
FBXO7
FCGR2A
FFAR2
FNDC9
FUT7
GJB1
GORAB
GPR42
IFNGR2
ITM2C
KASH5
KIR2DL3
LDLRAD1
LEUTX
LRRC25
LSMEM2
MR1
MTIF3
MUC1
NEMP1
PAX8
PF4
PPBP
PTPN5
RHCG
SFTPC
SLC10A1
SLC39A1
SSMEM1
SUSD3
SYNE4
TM4SF18
TMED5
TMEM106C
TMEM234
TMEM237
TMEM31
TMPRSS2
TNFSF14
TNFSF8
TSPAN18
XCL1
Entrez ID
7113
4283
HPRD ID
03637
03416
Ensembl ID
ENSG00000184012
ENSG00000138755
Uniprot IDs
O15393
Q07325
PDB IDs
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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