TMEM218 and GPR61

Data Source:
BioGRID (two hybrid)

		TMEM218	GPR61
Description		transmembrane protein 218	G protein-coupled receptor 61
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cilium Integral Component Of Membrane	Endosome Plasma Membrane Endosome Membrane Integral Component Of Membrane Receptor Complex
	Molecular Function	Protein Binding	G Protein-coupled Receptor Activity Protein Binding Arrestin Family Protein Binding
	Biological Process		G Protein-coupled Receptor Signaling Pathway Positive Regulation Of CAMP-mediated Signaling
Pathways
Drugs
Diseases
GWAS		Breast cancer (survival) ( 25890600) Familial lung adenocarcinoma ( 29924316)	Adult body size ( 32376654) Body mass index ( 28448500) Body mass index (joint analysis main effects and physical activity interaction) ( 28448500) Body mass index in physically active individuals ( 28448500) Body size at age 10 ( 32376654) Childhood body mass index ( 26604143) Chronotype ( 30696823) Hepcidin/ferritin ratio ( 27846281) Morning person ( 30696823) Stearic acid (18:0) levels ( 23362303) Waist circumference ( 25673412)
Interacting Genes		72 interacting genes: APH1A AQP2 AQP6 ARL13B ASZ1 ATP6V0E1 BSCL2 CD300A CD53 CD79A CLDN2 CLEC10A CLEC17A CPLX4 CREB3L1 CTLA4 DAGLA EBP ELOVL2 ELOVL4 EMP1 ERGIC3 FAM209A FCER1G FRMD3 GDAP1 GJB1 GJB4 GJB6 GPR152 GPR61 GPX8 IFNGR2 KCNJ6 KCNK5 KIR2DL3 LDLRAD1 LHFPL5 LMNA LSMEM2 MFF MS4A3 MTIF3 NPFFR2 PCNA PDCD1LG2 PIK3IP1 PLEKHO1 PSCA RETREG3 SAR1A SDC3 SLC10A4 SLC10A6 SLC18A1 SMIM3 SSMEM1 TM4SF18 TMED8 TMEM106C TMEM182 TMEM207 TMEM234 TMEM31 TMEM45B TMEM52B TMEM88 TMPRSS2 TRHR TSPAN12 TSPAN18 VSIR	20 interacting genes: APP ARL6IP6 ATP6V0B C4orf3 CLDND1 CTXN3 EMP3 FCER1G GJA8 GJB6 KLRC1 PLP1 PMP22 SCN3B SLC12A7 SLC13A4 STRIT1 TMEM147 TMEM218 TRARG1
Entrez ID		219854	83873
HPRD ID		19054	06077
Ensembl ID		ENSG00000150433	ENSG00000156097
Uniprot IDs		A2RU14	G4XH66 Q9BZJ8
PDB IDs
Enriched GO Terms of Interacting Partners?
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