Wiki-MPM
About
Search
Browse
People
Funding
Updates
Search
TJP1 and GJA8
Data Source:
HPRD
(in vivo, in vitro)
TJP1
GJA8
Description
tight junction protein 1
gap junction protein alpha 8
Image
No pdb structure
GO Annotations
Cellular Component
Podosome
Cytoplasm
Cytosol
Plasma Membrane
Adherens Junction
Gap Junction
Bicellular Tight Junction
Basolateral Plasma Membrane
Cell Junction
Protein-containing Complex
Cell Projection
Apical Junction Complex
Apical Part Of Cell
Tight Junction
Integral Component Of Plasma Membrane
Connexin Complex
Molecular Function
Protein Binding
Calmodulin Binding
Cadherin Binding
Cell Adhesion Molecule Binding
Gap Junction Channel Activity
Protein Binding
Identical Protein Binding
Biological Process
Cell-cell Junction Assembly
Positive Regulation Of Cell Population Proliferation
Positive Regulation Of Cell Migration
Actomyosin Structure Organization
Adherens Junction Maintenance
Hippo Signaling
Maintenance Of Blood-brain Barrier
Negative Regulation Of Apoptotic Process
Cell-cell Junction Organization
Regulation Of Cytoskeleton Organization
Negative Regulation Of Stress Fiber Assembly
Protein Localization To Adherens Junction
Establishment Of Endothelial Intestinal Barrier
Cell-cell Adhesion
Protein Localization To Cell-cell Junction
Regulation Of Cell Junction Assembly
Protein Localization To Bicellular Tight Junction
Positive Regulation Of Sprouting Angiogenesis
Positive Regulation Of Blood-brain Barrier Permeability
Positive Regulation Of Cell-cell Adhesion Mediated By Cadherin
Negative Regulation Of Actin Cytoskeleton Reorganization
Regulation Of Bicellular Tight Junction Assembly
Lens Development In Camera-type Eye
Cell-cell Signaling
Transmembrane Transport
Gap Junction-mediated Intercellular Transport
Pathways
Regulation of gap junction activity
Regulation of gap junction activity
Signaling by Hippo
Apoptotic cleavage of cell adhesion proteins
RUNX1 regulates expression of components of tight junctions
Gap junction assembly
Drugs
Diseases
GWAS
Central corneal thickness (
32528159
31798171
29760442
30894546
)
Corneal structure (
23291589
)
Response to antipsychotic treatment (
23241943
)
Retinopathy x type 2 diabetes interaction (
32541925
)
Interacting Genes
40 interacting genes:
ACTA1
ACTN4
AFDN
ARVCF
CGN
CLDN1
CLDN16
CLDN2
CLDN3
CLDN4
CLDN5
CLDN6
CLDN7
CLDN8
CNKSR2
CTNNA1
CTTN
EGFR
F11R
GJA1
GJA3
GJA8
GJB3
GJC1
GJD3
GRIN1
GRIN2D
HSP90AA1
JAM2
JAM3
KHDRBS1
KIRREL1
OCLN
PEA15
PTPN14
TJP2
TJP3
TRPC4
UBN1
YBX3
121 interacting genes:
ABL1
ACKR2
APOA2
APOD
APOL3
AQP4
ARL6IP6
ATP6V0B
C1GALT1
C2CD2L
C3orf52
CCDC167
CCL4
CD53
CIAO2A
CLDN19
CLDN4
CLEC1A
CLN6
COX20
CTXN3
CXCL16
CYBC1
CYP4F2
DEFB121
DOLK
ERMP1
FDFT1
FXYD6
GIMAP1
GIMAP5
GJB2
GPR108
GPR151
GPR61
GUCA2A
IGFBP5
INSIG2
ITGAM
KIR2DL3
LAPTM4B
LAT
LEPROTL1
LHFPL5
MAL
MALL
MARCHF2
MFSD11
MFSD6
MGST2
MIP
MS4A13
ORMDL2
OTOP2
P2RY13
PGAP2
PLN
PMP22
PNLIPRP1
PRAF2
PROKR2
PTPRN
QRFPR
REEP6
RNF152
RUSF1
RXFP4
S1PR5
SCARF1
SEC22B
SEC22C
SEC23A
SFTPC
SLC13A2
SLC13A5
SLC16A12
SLC16A13
SLC16A3
SLC30A3
SLC35A4
SLC35F1
SLC35F6
SLC38A4
SLC38A7
SLC39A2
SLC39A7
SLC39A9
SLC52A1
SLC66A1
SLC66A2
SLC8A3
SMCO4
SMIM1
STX1B
STX8
THSD7B
TJP1
TMBIM6
TMEM100
TMEM107
TMEM121
TMEM128
TMEM147
TMEM182
TMEM239
TMEM242
TMEM243
TMEM42
TMEM45A
TMEM60
TMEM65
TMEM72
TMEM86B
TSPAN33
TWSG1
UBXN8
UNC93A
UPK1B
VAMP5
YIF1A
YIPF6
Entrez ID
7082
2703
HPRD ID
03002
02939
Ensembl ID
ENSG00000104067
ENSG00000121634
Uniprot IDs
A9CQZ8
B4DZK4
G3V1L9
G5E9E7
Q07157
Q6MZU1
P48165
X5D7G1
PDB IDs
2H2B
2H2C
2H3M
2JWE
2KXR
2KXS
2RCZ
3CYY
3LH5
3SHU
3SHW
3TSV
3TSW
3TSZ
4OEO
4OEP
4Q2Q
4YYX
Enriched GO Terms of Interacting Partners
?
Tagcloud
?
Tagcloud (Difference)
?
Tagcloud (Intersection)
?