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TJP1 and CLDN4
Data Source:
BioGRID
(pull down)
HPRD
(in vitro)
TJP1
CLDN4
Description
tight junction protein 1
claudin 4
Image
GO Annotations
Cellular Component
Podosome
Cytoplasm
Cytosol
Plasma Membrane
Adherens Junction
Gap Junction
Bicellular Tight Junction
Basolateral Plasma Membrane
Cell Junction
Protein-containing Complex
Cell Projection
Apical Junction Complex
Apical Part Of Cell
Tight Junction
Plasma Membrane
Integral Component Of Plasma Membrane
Cell-cell Junction
Bicellular Tight Junction
Basal Plasma Membrane
Apical Plasma Membrane
Apicolateral Plasma Membrane
Lateral Plasma Membrane
Chloride Channel Complex
Tight Junction
Molecular Function
Protein Binding
Calmodulin Binding
Cadherin Binding
Cell Adhesion Molecule Binding
Transmembrane Signaling Receptor Activity
Structural Molecule Activity
Chloride Channel Activity
Protein Binding
Identical Protein Binding
Biological Process
Cell-cell Junction Assembly
Positive Regulation Of Cell Population Proliferation
Positive Regulation Of Cell Migration
Actomyosin Structure Organization
Adherens Junction Maintenance
Hippo Signaling
Maintenance Of Blood-brain Barrier
Negative Regulation Of Apoptotic Process
Cell-cell Junction Organization
Regulation Of Cytoskeleton Organization
Negative Regulation Of Stress Fiber Assembly
Protein Localization To Adherens Junction
Establishment Of Endothelial Intestinal Barrier
Cell-cell Adhesion
Protein Localization To Cell-cell Junction
Regulation Of Cell Junction Assembly
Protein Localization To Bicellular Tight Junction
Positive Regulation Of Sprouting Angiogenesis
Positive Regulation Of Blood-brain Barrier Permeability
Positive Regulation Of Cell-cell Adhesion Mediated By Cadherin
Negative Regulation Of Actin Cytoskeleton Reorganization
Regulation Of Bicellular Tight Junction Assembly
Cell Adhesion
Female Pregnancy
Circadian Rhythm
Calcium-independent Cell-cell Adhesion Via Plasma Membrane Cell-adhesion Molecules
Regulation Of Cell Morphogenesis
Positive Regulation Of Cell Migration
Response To Progesterone
Establishment Of Skin Barrier
Renal Absorption
Bicellular Tight Junction Assembly
Positive Regulation Of Wound Healing
Chloride Transmembrane Transport
Positive Regulation Of Metallopeptidase Activity
Pathways
Regulation of gap junction activity
Regulation of gap junction activity
Signaling by Hippo
Apoptotic cleavage of cell adhesion proteins
RUNX1 regulates expression of components of tight junctions
Tight junction interactions
Drugs
Diseases
GWAS
Central corneal thickness (
32528159
31798171
29760442
30894546
)
Corneal structure (
23291589
)
Response to antipsychotic treatment (
23241943
)
Interacting Genes
40 interacting genes:
ACTA1
ACTN4
AFDN
ARVCF
CGN
CLDN1
CLDN16
CLDN2
CLDN3
CLDN4
CLDN5
CLDN6
CLDN7
CLDN8
CNKSR2
CTNNA1
CTTN
EGFR
F11R
GJA1
GJA3
GJA8
GJB3
GJC1
GJD3
GRIN1
GRIN2D
HSP90AA1
JAM2
JAM3
KHDRBS1
KIRREL1
OCLN
PEA15
PTPN14
TJP2
TJP3
TRPC4
UBN1
YBX3
19 interacting genes:
AQP6
ARL13B
CLEC14A
EPHA2
FAM209A
FFAR2
GJA8
GOLM1
HSD17B13
ICAM3
MFSD14B
SHBG
SYT2
TJP1
TMEM237
TMEM52B
TRIM59
TSPO2
WNK4
Entrez ID
7082
1364
HPRD ID
03002
04218
Ensembl ID
ENSG00000104067
ENSG00000189143
Uniprot IDs
A9CQZ8
B4DZK4
G3V1L9
G5E9E7
Q07157
Q6MZU1
O14493
Q75L80
PDB IDs
2H2B
2H2C
2H3M
2JWE
2KXR
2KXS
2RCZ
3CYY
3LH5
3SHU
3SHW
3TSV
3TSW
3TSZ
4OEO
4OEP
4Q2Q
4YYX
5B2G
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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