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TJP1 and YBX3
Data Source:
BioGRID
(pull down)
TJP1
YBX3
Description
tight junction protein 1
Y-box binding protein 3
Image
No pdb structure
GO Annotations
Cellular Component
Podosome
Cytoplasm
Cytosol
Plasma Membrane
Adherens Junction
Gap Junction
Bicellular Tight Junction
Basolateral Plasma Membrane
Cell Junction
Protein-containing Complex
Cell Projection
Apical Junction Complex
Apical Part Of Cell
Tight Junction
Nucleus
Cytoplasm
Cytosol
Bicellular Tight Junction
Perinuclear Region Of Cytoplasm
Molecular Function
Protein Binding
Calmodulin Binding
Cadherin Binding
Cell Adhesion Molecule Binding
RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific
Nucleic Acid Binding
RNA Binding
MRNA 3'-UTR Binding
Protein Binding
Small GTPase Binding
Polysome Binding
Biological Process
Cell-cell Junction Assembly
Positive Regulation Of Cell Population Proliferation
Positive Regulation Of Cell Migration
Actomyosin Structure Organization
Adherens Junction Maintenance
Hippo Signaling
Maintenance Of Blood-brain Barrier
Negative Regulation Of Apoptotic Process
Cell-cell Junction Organization
Regulation Of Cytoskeleton Organization
Negative Regulation Of Stress Fiber Assembly
Protein Localization To Adherens Junction
Establishment Of Endothelial Intestinal Barrier
Cell-cell Adhesion
Protein Localization To Cell-cell Junction
Regulation Of Cell Junction Assembly
Protein Localization To Bicellular Tight Junction
Positive Regulation Of Sprouting Angiogenesis
Positive Regulation Of Blood-brain Barrier Permeability
Positive Regulation Of Cell-cell Adhesion Mediated By Cadherin
Negative Regulation Of Actin Cytoskeleton Reorganization
Regulation Of Bicellular Tight Junction Assembly
Negative Regulation Of Transcription By RNA Polymerase II
In Utero Embryonic Development
Spermatogenesis
Male Gonad Development
Fertilization
Regulation Of Gene Expression
Positive Regulation Of Organ Growth
Negative Regulation Of Skeletal Muscle Tissue Development
Negative Regulation Of Necroptotic Process
3'-UTR-mediated MRNA Stabilization
Cellular Response To Tumor Necrosis Factor
Cellular Hyperosmotic Response
Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To Osmotic Stress
Positive Regulation Of Cytoplasmic Translation
Pathways
Regulation of gap junction activity
Regulation of gap junction activity
Signaling by Hippo
Apoptotic cleavage of cell adhesion proteins
RUNX1 regulates expression of components of tight junctions
Drugs
Diseases
GWAS
Central corneal thickness (
32528159
31798171
29760442
30894546
)
Corneal structure (
23291589
)
Response to antipsychotic treatment (
23241943
)
Coronary artery disease (
33020668
)
Refractive error (
32231278
)
Interacting Genes
40 interacting genes:
ACTA1
ACTN4
AFDN
ARVCF
CGN
CLDN1
CLDN16
CLDN2
CLDN3
CLDN4
CLDN5
CLDN6
CLDN7
CLDN8
CNKSR2
CTNNA1
CTTN
EGFR
F11R
GJA1
GJA3
GJA8
GJB3
GJC1
GJD3
GRIN1
GRIN2D
HSP90AA1
JAM2
JAM3
KHDRBS1
KIRREL1
OCLN
PEA15
PTPN14
TJP2
TJP3
TRPC4
UBN1
YBX3
84 interacting genes:
CDK4
CDK5
GSK3B
IL7R
MAPK1
MIR1-1
MIR1-2
MIR106A
MIR106B
MIR107
MIR10B
MIR122
MIR128-1
MIR128-2
MIR138-1
MIR138-2
MIR140
MIR141
MIR143
MIR145
MIR155
MIR15A
MIR15B
MIR16-1
MIR16-2
MIR17
MIR18A
MIR18B
MIR199A1
MIR199A2
MIR19A
MIR19B1
MIR19B2
MIR200A
MIR200B
MIR200C
MIR205
MIR206
MIR20A
MIR20B
MIR21
MIR214
MIR221
MIR222
MIR25
MIR29A
MIR29B1
MIR29B2
MIR29C
MIR31
MIR34A
MIR34B
MIR34C
MIR363
MIR429
MIR451A
MIR7-1
MIR7-2
MIR7-3
MIR9-1
MIR9-2
MIR9-3
MIR92A1
MIR92A2
MIR93
MIR98
MIRLET7A1
MIRLET7A2
MIRLET7A3
MIRLET7B
MIRLET7C
MIRLET7D
MIRLET7E
MIRLET7F1
MIRLET7F2
MIRLET7G
MIRLET7I
NFYB
PCBP2
RALA
SRPK2
SYMPK
TJP1
VEGFA
Entrez ID
7082
8531
HPRD ID
03002
10347
Ensembl ID
ENSG00000104067
ENSG00000060138
Uniprot IDs
A9CQZ8
B4DZK4
G3V1L9
G5E9E7
Q07157
Q6MZU1
A0A024RAQ1
A0A024RAV4
P16989
PDB IDs
2H2B
2H2C
2H3M
2JWE
2KXR
2KXS
2RCZ
3CYY
3LH5
3SHU
3SHW
3TSV
3TSW
3TSZ
4OEO
4OEP
4Q2Q
4YYX
Enriched GO Terms of Interacting Partners
?
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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