TARBP2 and HDHD2

Data Source:
HPRD (two hybrid)

		TARBP2	HDHD2
Description		TARBP2 subunit of RISC loading complex	haloacid dehalogenase like hydrolase domain containing 2
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GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Cytosol RISC Complex Nuclear Body Perinuclear Region Of Cytoplasm RISC-loading Complex	Extracellular Exosome
	Molecular Function	Double-stranded RNA Binding Protein Binding Enzyme Binding SiRNA Binding MiRNA Binding Pre-mRNA Binding Identical Protein Binding Protein Homodimerization Activity Protein N-terminus Binding Pre-miRNA Binding	Protein Binding Phosphatase Activity Enzyme Binding Metal Ion Binding
	Biological Process	Negative Regulation Of Protein Kinase Activity Spermatid Development Single Fertilization MiRNA Metabolic Process Production Of SiRNA Involved In RNA Interference Targeting Of MRNA For Destruction Involved In RNA Interference Pre-miRNA Processing SiRNA Loading Onto RISC Involved In RNA Interference Production Of MiRNAs Involved In Gene Silencing By MiRNA Multicellular Organism Growth MiRNA Loading Onto RISC Involved In Gene Silencing By MiRNA Skeletal Muscle Tissue Regeneration Positive Regulation Of Viral Genome Replication Positive Regulation Of Translation Regulation Of Viral Transcription Negative Regulation Of Defense Response To Virus By Host Positive Regulation Of Muscle Cell Differentiation Neural Precursor Cell Proliferation Regulation Of Production Of SiRNA Involved In RNA Interference Regulation Of Production Of MiRNAs Involved In Gene Silencing By MiRNA	Biological_process Dephosphorylation
Pathways		MicroRNA (miRNA) biogenesis Small interfering RNA (siRNA) biogenesis
Drugs
Diseases
GWAS		Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)	Blood protein levels ( 30072576 29875488) Fruit consumption ( 32066663)
Interacting Genes		27 interacting genes: ADARB1 AGO2 APP DICER1 EIF2AK2 HDHD2 HSPB1 IKBKG KCNIP3 MAPK8IP2 MED21 NEDD4L NEUROG1 NF2 NUDT18 PNKP PRKRA RBM14 TCEA2 TCEANC TGIF2 TOP1 TRAF4 VAV2 ZMAT3 ZMAT4 ZNF346	12 interacting genes: ADGRB2 CFD CRMP1 DVL1 EPHB6 LUC7L2 MEOX2 MGST2 PIP5K1C SOD2 TARBP2 TRAPPC11
Entrez ID		6895	84064
HPRD ID		05446	13640
Ensembl ID		ENSG00000139546	ENSG00000167220
Uniprot IDs		A0A024RB49 Q15633	Q9H0R4 V9HW73
PDB IDs		2CPN 3ADL 3LLH 4WYQ 5N8L 5N8M 5ZAK 5ZAL 5ZAM	3HLT
Enriched GO Terms of Interacting Partners?
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