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TARBP2 and MED21
Data Source:
BioGRID
(two hybrid)
TARBP2
MED21
Description
TARBP2 subunit of RISC loading complex
mediator complex subunit 21
Image
No pdb structure
GO Annotations
Cellular Component
Nucleoplasm
Cytoplasm
Cytosol
RISC Complex
Nuclear Body
Perinuclear Region Of Cytoplasm
RISC-loading Complex
Mediator Complex
Molecular Function
Double-stranded RNA Binding
Protein Binding
Enzyme Binding
SiRNA Binding
MiRNA Binding
Pre-mRNA Binding
Identical Protein Binding
Protein Homodimerization Activity
Protein N-terminus Binding
Pre-miRNA Binding
Transcription Coregulator Activity
Transcription Coactivator Activity
DNA-directed 5'-3' RNA Polymerase Activity
Protein Binding
Biological Process
Negative Regulation Of Protein Kinase Activity
Spermatid Development
Single Fertilization
MiRNA Metabolic Process
Production Of SiRNA Involved In RNA Interference
Targeting Of MRNA For Destruction Involved In RNA Interference
Pre-miRNA Processing
SiRNA Loading Onto RISC Involved In RNA Interference
Production Of MiRNAs Involved In Gene Silencing By MiRNA
Multicellular Organism Growth
MiRNA Loading Onto RISC Involved In Gene Silencing By MiRNA
Skeletal Muscle Tissue Regeneration
Positive Regulation Of Viral Genome Replication
Positive Regulation Of Translation
Regulation Of Viral Transcription
Negative Regulation Of Defense Response To Virus By Host
Positive Regulation Of Muscle Cell Differentiation
Neural Precursor Cell Proliferation
Regulation Of Production Of SiRNA Involved In RNA Interference
Regulation Of Production Of MiRNAs Involved In Gene Silencing By MiRNA
Regulation Of Transcription By RNA Polymerase II
RNA Biosynthetic Process
Positive Regulation Of Transcription By RNA Polymerase II
Pathways
MicroRNA (miRNA) biogenesis
Small interfering RNA (siRNA) biogenesis
PPARA activates gene expression
Transcriptional regulation of white adipocyte differentiation
Transcriptional regulation of white adipocyte differentiation
Drugs
Diseases
GWAS
Waist-to-hip ratio adjusted for BMI (
26426971
)
Waist-to-hip ratio adjusted for BMI (age <50) (
26426971
)
Waist-to-hip ratio adjusted for BMI (age >50) (
26426971
)
Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) (
26426971
)
Dimensional psychopathology (Social) (
29496196
)
Interacting Genes
27 interacting genes:
ADARB1
AGO2
APP
DICER1
EIF2AK2
HDHD2
HSPB1
IKBKG
KCNIP3
MAPK8IP2
MED21
NEDD4L
NEUROG1
NF2
NUDT18
PNKP
PRKRA
RBM14
TCEA2
TCEANC
TGIF2
TOP1
TRAF4
VAV2
ZMAT3
ZMAT4
ZNF346
30 interacting genes:
BLOC1S6
BORCS6
BRCA1
BTF3
CDK8
CDK9
ELOA
ESR1
ESR2
HGS
HNF4A
HTT
MAGEA6
MAGEB4
MED29
MIEF1
PCBD2
POLR2A
SKP1
SSC5D
TARBP2
TFG
THRA
THRB
TP53
TRIM27
TRIM72
VAV2
ZNF655
ZSCAN1
Entrez ID
6895
9412
HPRD ID
05446
09156
Ensembl ID
ENSG00000139546
ENSG00000152944
Uniprot IDs
A0A024RB49
Q15633
A0A024RAW0
Q13503
PDB IDs
2CPN
3ADL
3LLH
4WYQ
5N8L
5N8M
5ZAK
5ZAL
5ZAM
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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