HDHD2 and CFD

Data Source:
HPRD (two hybrid)

		HDHD2	CFD
Description		haloacid dehalogenase like hydrolase domain containing 2	complement factor D
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GO Annotations	Cellular Component	Extracellular Exosome	Extracellular Region Platelet Alpha Granule Lumen Secretory Granule Lumen Extracellular Exosome Ficolin-1-rich Granule Lumen
	Molecular Function	Protein Binding Phosphatase Activity Enzyme Binding Metal Ion Binding	Serine-type Endopeptidase Activity Serine-type Peptidase Activity
	Biological Process	Biological_process Dephosphorylation	Platelet Degranulation Proteolysis Complement Activation Complement Activation, Alternative Pathway Notch Signaling Pathway Neutrophil Degranulation
Pathways			Platelet degranulation Alternative complement activation Neutrophil degranulation
Drugs			2-Aminobenzyl alcohol 3,4-Dichloroisocoumarin
Diseases			Alternative complement pathway component defects, including the following four diseases: Factor B deficiency; Factor D deficiency; Factor H deficiency; Properdin deficiency
GWAS		Blood protein levels ( 30072576 29875488) Fruit consumption ( 32066663)	High light scatter reticulocyte percentage of red cells ( 32888494) Reticulocyte count ( 32888494)
Interacting Genes		12 interacting genes: ADGRB2 CFD CRMP1 DVL1 EPHB6 LUC7L2 MEOX2 MGST2 PIP5K1C SOD2 TARBP2 TRAPPC11	2 interacting genes: HDHD2 SERPINF2
Entrez ID		84064	1675
HPRD ID		13640	00600
Ensembl ID		ENSG00000167220	ENSG00000197766
Uniprot IDs		Q9H0R4 V9HW73	A6XNE2 K7ERG9 P00746
PDB IDs		3HLT	1BIO 1DFP 1DIC 1DST 1DSU 1FDP 1HFD 2XW9 2XWA 2XWB 4CBN 4CBO 4D9R 5FBE 5FBI 5FCK 5MT0 5MT4 5NAR 5NAT 5NAW 5NB6 5NB7 5NBA 5TCA 5TCC 6FTY 6FTZ 6FUG 6FUH 6FUI 6FUJ 6FUT 6QMR 6QMT
Enriched GO Terms of Interacting Partners?
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