HDHD2 and EPHB6

Data Source:
HPRD (two hybrid)

		HDHD2	EPHB6
Description		haloacid dehalogenase like hydrolase domain containing 2	EPH receptor B6
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Exosome	Extracellular Region Cytosol Plasma Membrane Integral Component Of Plasma Membrane Neuron Projection Receptor Complex
	Molecular Function	Protein Binding Phosphatase Activity Enzyme Binding Metal Ion Binding	Transmembrane Receptor Protein Tyrosine Kinase Activity Ephrin Receptor Activity Transmembrane-ephrin Receptor Activity ATP Binding Signaling Receptor Activity
	Biological Process	Biological_process Dephosphorylation	Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Multicellular Organism Development Axon Guidance Peptidyl-tyrosine Phosphorylation Central Nervous System Projection Neuron Axonogenesis Positive Regulation Of Kinase Activity Ephrin Receptor Signaling Pathway
Pathways			EPH-Ephrin signaling EPH-Ephrin signaling EPHB-mediated forward signaling EPHB-mediated forward signaling Ephrin signaling Ephrin signaling EPH-ephrin mediated repulsion of cells
Drugs			Fostamatinib
Diseases
GWAS		Blood protein levels ( 30072576 29875488) Fruit consumption ( 32066663)	Alcoholic chronic pancreatitis ( 28754779) Blood protein levels ( 30072576 29875488) Cancer ( 29299148)
Interacting Genes		12 interacting genes: ADGRB2 CFD CRMP1 DVL1 EPHB6 LUC7L2 MEOX2 MGST2 PIP5K1C SOD2 TARBP2 TRAPPC11	27 interacting genes: AFDN ASB12 CBL CRK CRKL DDIT4L DUSP18 DUSP19 EFNB2 EPHB1 ERBB2 GRB2 HDHD2 INCA1 MSX2 MTARC1 NIF3L1 NOTCH2NLA POU6F2 PRMT5 REL SAT1 STYX TCF4 TEKT5 TRIB3 TRIM39
Entrez ID		84064	2051
HPRD ID		13640	04133
Ensembl ID		ENSG00000167220	ENSG00000106123
Uniprot IDs		Q9H0R4 V9HW73	F8WCM8 J3KQU5 O15197
PDB IDs		3HLT
Enriched GO Terms of Interacting Partners?
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