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TARBP2 and TGIF2
Data Source:
BioGRID
(two hybrid)
TARBP2
TGIF2
Description
TARBP2 subunit of RISC loading complex
TGFB induced factor homeobox 2
Image
No pdb structure
GO Annotations
Cellular Component
Nucleoplasm
Cytoplasm
Cytosol
RISC Complex
Nuclear Body
Perinuclear Region Of Cytoplasm
RISC-loading Complex
Chromatin
Nucleus
Nucleoplasm
Centrosome
Molecular Function
Double-stranded RNA Binding
Protein Binding
Enzyme Binding
SiRNA Binding
MiRNA Binding
Pre-mRNA Binding
Identical Protein Binding
Protein Homodimerization Activity
Protein N-terminus Binding
Pre-miRNA Binding
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
DNA-binding Transcription Factor Activity
Sequence-specific Double-stranded DNA Binding
Biological Process
Negative Regulation Of Protein Kinase Activity
Spermatid Development
Single Fertilization
MiRNA Metabolic Process
Production Of SiRNA Involved In RNA Interference
Targeting Of MRNA For Destruction Involved In RNA Interference
Pre-miRNA Processing
SiRNA Loading Onto RISC Involved In RNA Interference
Production Of MiRNAs Involved In Gene Silencing By MiRNA
Multicellular Organism Growth
MiRNA Loading Onto RISC Involved In Gene Silencing By MiRNA
Skeletal Muscle Tissue Regeneration
Positive Regulation Of Viral Genome Replication
Positive Regulation Of Translation
Regulation Of Viral Transcription
Negative Regulation Of Defense Response To Virus By Host
Positive Regulation Of Muscle Cell Differentiation
Neural Precursor Cell Proliferation
Regulation Of Production Of SiRNA Involved In RNA Interference
Regulation Of Production Of MiRNAs Involved In Gene Silencing By MiRNA
Negative Regulation Of Transcription By RNA Polymerase II
Regulation Of Transcription, DNA-templated
Regulation Of Transcription By RNA Polymerase II
Regulation Of Gastrulation
Nodal Signaling Pathway
Positive Regulation Of Neuron Differentiation
Retina Development In Camera-type Eye
Pathways
MicroRNA (miRNA) biogenesis
Small interfering RNA (siRNA) biogenesis
Downregulation of SMAD2/3:SMAD4 transcriptional activity
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
Drugs
Diseases
GWAS
Waist-to-hip ratio adjusted for BMI (
26426971
)
Waist-to-hip ratio adjusted for BMI (age <50) (
26426971
)
Waist-to-hip ratio adjusted for BMI (age >50) (
26426971
)
Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) (
26426971
)
Interacting Genes
27 interacting genes:
ADARB1
AGO2
APP
DICER1
EIF2AK2
HDHD2
HSPB1
IKBKG
KCNIP3
MAPK8IP2
MED21
NEDD4L
NEUROG1
NF2
NUDT18
PNKP
PRKRA
RBM14
TCEA2
TCEANC
TGIF2
TOP1
TRAF4
VAV2
ZMAT3
ZMAT4
ZNF346
5 interacting genes:
FBXO7
HDAC1
RBBP8
SMAD3
TARBP2
Entrez ID
6895
60436
HPRD ID
05446
06293
Ensembl ID
ENSG00000139546
ENSG00000118707
Uniprot IDs
A0A024RB49
Q15633
Q9GZN2
PDB IDs
2CPN
3ADL
3LLH
4WYQ
5N8L
5N8M
5ZAK
5ZAL
5ZAM
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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