SYTL4 and RAB3D

Data Source:
BioGRID (two hybrid)

		SYTL4	RAB3D
Description		synaptotagmin like 4	RAB3D, member RAS oncogene family
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GO Annotations	Cellular Component	Endosome Plasma Membrane Extrinsic Component Of Membrane Transport Vesicle Membrane Platelet Alpha Granule Membrane Exocytic Vesicle	Endosome Cytoplasmic Microtubule Plasma Membrane Synaptic Vesicle Azurophil Granule Membrane Zymogen Granule Extracellular Exosome Secretory Vesicle
	Molecular Function	Protein Binding Phospholipid Binding Neurexin Family Protein Binding Metal Ion Binding	GTPase Activity Protein Binding GTP Binding GTP-dependent Protein Binding Myosin V Binding
	Biological Process	Plasma Membrane Repair Platelet Degranulation Intracellular Protein Transport Exocytosis Lysosome Localization Positive Regulation Of Exocytosis Negative Regulation Of Insulin Secretion Positive Regulation Of Protein Secretion Multivesicular Body Sorting Pathway Regulation Of Plasma Membrane Repair	Vesicle Docking Involved In Exocytosis Protein Secretion Regulation Of Exocytosis Peptidyl-cysteine Methylation Neutrophil Degranulation Bone Resorption Protein Localization To Plasma Membrane Positive Regulation Of Regulated Secretory Pathway
Pathways		Platelet degranulation	Neutrophil degranulation RAB geranylgeranylation
Drugs		Insulin pork
Diseases
GWAS		Lean body mass ( 28552196) Mean platelet volume ( 32888494) Platelet distribution width ( 32888494)	Early cardiac repolarization ( 31600170) HDL cholesterol ( 23505323)
Interacting Genes		27 interacting genes: CCDC85B CEP70 DVL3 FCHO1 FXR2 HMG20A INS KIFC3 LMO1 LZTS1 OSBPL3 PRKAR1B RAB27A RAB27B RAB3A RAB3D RAB8A ROPN1 SPANXN2 STX1A STXBP1 TBC1D1 TRIM37 TRIM41 ZBTB7B ZBTB9 ZRANB1	15 interacting genes: AKT1 AKT2 AP1M2 APP CEP55 CHM CYP2C9 MAST1 RAB3IP RABIF RIMS2 RNF32 RPH3AL SYTL4 VRTN
Entrez ID		94121	9545
HPRD ID		06735	05070
Ensembl ID		ENSG00000102362	ENSG00000105514
Uniprot IDs		A0A024RCF8 A8K973 B2R7R4 Q71SF7 Q96C24	A0A024R7G2 O95716
PDB IDs		2CSZ 3FDW 5X6T	2GF9
Enriched GO Terms of Interacting Partners?
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