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TBC1D15 and FIS1
Data Source:
BioGRID
(proximity labelling technology, affinity chromatography technology, pull down)
TBC1D15
FIS1
Description
TBC1 domain family member 15
fission, mitochondrial 1
Image
No pdb structure
GO Annotations
Cellular Component
Extracellular Region
Cytoplasm
Mitochondrion
Peroxisome
Integral Component Of Peroxisomal Membrane
Endoplasmic Reticulum
Membrane
Integral Component Of Mitochondrial Outer Membrane
Protein-containing Complex
Molecular Function
GTPase Activator Activity
Protein Binding
Protein Binding
Identical Protein Binding
Biological Process
Intracellular Protein Transport
Regulation Of GTPase Activity
Activation Of GTPase Activity
Regulation Of Cilium Assembly
Mitochondrial Fission
Autophagy Of Mitochondrion
Release Of Cytochrome C From Mitochondria
Protein Targeting To Mitochondrion
Positive Regulation Of Cytosolic Calcium Ion Concentration
Mitochondrial Fusion
Regulation Of Mitochondrion Organization
Peroxisome Fission
Negative Regulation Of Endoplasmic Reticulum Calcium Ion Concentration
Calcium-mediated Signaling Using Intracellular Calcium Source
Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Mitochondrial Fragmentation Involved In Apoptotic Process
Positive Regulation Of Mitochondrial Calcium Ion Concentration
Mitochondrion Morphogenesis
Positive Regulation Of Mitochondrial Fission
Positive Regulation Of Protein Targeting To Membrane
Negative Regulation Of ATP Metabolic Process
Negative Regulation Of Fatty Acid Transport
Positive Regulation Of Intrinsic Apoptotic Signaling Pathway
Pathways
TBC/RABGAPs
Class I peroxisomal membrane protein import
Drugs
Diseases
GWAS
Inferior parietal cortex volume (
31530798
)
Metabolite levels (
23823483
)
Rheumatoid arthritis (
30891314
)
Interacting Genes
9 interacting genes:
CALCOCO1
CEP63
FIS1
OPTN
RAB5A
RAB5B
RAB5C
TAX1BP1
UBC
30 interacting genes:
A2M
ABHD6
APH1A
BCAP31
CREB3
DNM1L
EBP
ERGIC3
FAM209A
FAM210B
FFAR2
JAGN1
KASH5
KCNJ6
MARCHF5
MMGT1
NOS3
PIGP
RNASEK
SCN3B
SLC10A6
SLC14A1
SLC22A1
SLC22A2
SPCS1
TBC1D15
TMEM14B
TMPPE
UBC
VKORC1
Entrez ID
64786
51024
HPRD ID
15470
12352
Ensembl ID
ENSG00000121749
ENSG00000214253
Uniprot IDs
A8K8E1
Q8TC07
Q9Y3D6
PDB IDs
1NZN
1PC2
Enriched GO Terms of Interacting Partners
?
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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