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FIS1 and DNM1L
Data Source:
HPRD
(in vitro, in vivo)
FIS1
DNM1L
Description
fission, mitochondrial 1
dynamin 1 like
Image
GO Annotations
Cellular Component
Mitochondrion
Peroxisome
Integral Component Of Peroxisomal Membrane
Endoplasmic Reticulum
Membrane
Integral Component Of Mitochondrial Outer Membrane
Protein-containing Complex
Golgi Membrane
Cytoplasm
Mitochondrion
Mitochondrial Outer Membrane
Peroxisome
Endoplasmic Reticulum
Endoplasmic Reticulum Membrane
Golgi Apparatus
Cytosol
Microtubule
Brush Border
Clathrin-coated Pit
Membrane
Synaptic Vesicle Membrane
Mitochondrial Membrane
Protein-containing Complex
Intracellular Membrane-bounded Organelle
Perinuclear Region Of Cytoplasm
Presynaptic Endocytic Zone Membrane
Mitochondrion-derived Vesicle
Molecular Function
Protein Binding
Identical Protein Binding
GTPase Activity
GTPase Activator Activity
Protein Binding
GTP Binding
Microtubule Binding
Lipid Binding
Clathrin Binding
GTP-dependent Protein Binding
Small GTPase Binding
Ubiquitin Protein Ligase Binding
Identical Protein Binding
Protein Homodimerization Activity
Protein-containing Complex Binding
BH2 Domain Binding
Biological Process
Mitochondrial Fission
Autophagy Of Mitochondrion
Release Of Cytochrome C From Mitochondria
Protein Targeting To Mitochondrion
Positive Regulation Of Cytosolic Calcium Ion Concentration
Mitochondrial Fusion
Regulation Of Mitochondrion Organization
Peroxisome Fission
Negative Regulation Of Endoplasmic Reticulum Calcium Ion Concentration
Calcium-mediated Signaling Using Intracellular Calcium Source
Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Mitochondrial Fragmentation Involved In Apoptotic Process
Positive Regulation Of Mitochondrial Calcium Ion Concentration
Mitochondrion Morphogenesis
Positive Regulation Of Mitochondrial Fission
Positive Regulation Of Protein Targeting To Membrane
Negative Regulation Of ATP Metabolic Process
Negative Regulation Of Fatty Acid Transport
Positive Regulation Of Intrinsic Apoptotic Signaling Pathway
Mitochondrial Fission
Release Of Cytochrome C From Mitochondria
Dynamin Family Protein Polymerization Involved In Mitochondrial Fission
Calcium Ion Transport
Mitochondrion Organization
Endoplasmic Reticulum Organization
Regulation Of Gene Expression
Negative Regulation Of Mitochondrial Fusion
Regulation Of Mitochondrion Organization
Peroxisome Fission
Synaptic Vesicle Recycling Via Endosome
Positive Regulation Of Apoptotic Process
Positive Regulation Of GTPase Activity
Mitochondrial Fragmentation Involved In Apoptotic Process
Intracellular Distribution Of Mitochondria
Synaptic Vesicle Endocytosis
Rhythmic Process
Positive Regulation Of Protein Secretion
Protein Complex Oligomerization
Heart Contraction
Positive Regulation Of Dendritic Spine Morphogenesis
Membrane Fusion
Protein-containing Complex Assembly
Necroptotic Process
Mitochondrion Morphogenesis
Protein Localization To Mitochondrion
Positive Regulation Of Neutrophil Chemotaxis
Positive Regulation Of Mitochondrial Fission
Mitochondrial Membrane Fission
Positive Regulation Of Release Of Cytochrome C From Mitochondria
Cellular Response To Oxygen-glucose Deprivation
Execution Phase Of Apoptosis
Regulation Of Peroxisome Organization
Positive Regulation Of Synaptic Vesicle Endocytosis
Regulation Of Autophagy Of Mitochondrion
Regulation Of ATP Metabolic Process
Cellular Response To Thapsigargin
Regulation Of Ubiquitin Protein Ligase Activity
Response To Flavonoid
Response To Hypobaric Hypoxia
Positive Regulation Of Synaptic Vesicle Exocytosis
Positive Regulation Of Intrinsic Apoptotic Signaling Pathway
Pathways
Class I peroxisomal membrane protein import
Apoptotic execution phase
Drugs
Diseases
GWAS
Rheumatoid arthritis (
30891314
)
Mean platelet volume (
32888494
)
Platelet count (
32888494
)
Platelet distribution width (
32888494
)
Interacting Genes
30 interacting genes:
A2M
ABHD6
APH1A
BCAP31
CREB3
DNM1L
EBP
ERGIC3
FAM209A
FAM210B
FFAR2
JAGN1
KASH5
KCNJ6
MARCHF5
MMGT1
NOS3
PIGP
RNASEK
SCN3B
SLC10A6
SLC14A1
SLC22A1
SLC22A2
SPCS1
TBC1D15
TMEM14B
TMPPE
UBC
VKORC1
20 interacting genes:
FIS1
FZR1
GSK3B
MAGEA1
MAGEA3
MAP3K10
MFF
MIEF1
MIEF2
MUL1
PINK1
PRKN
RRM2
SCG3
SENP3
SH3GL1
SIRT3
SUMO2
VIM
ZBTB24
Entrez ID
51024
10059
HPRD ID
12352
04833
Ensembl ID
ENSG00000214253
ENSG00000087470
Uniprot IDs
Q9Y3D6
B4DYR6
O00429
PDB IDs
1NZN
1PC2
3W6N
3W6O
3W6P
4BEJ
4H1U
4H1V
5WP9
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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