FIS1 and PIGP

Data Source:
BioGRID (two hybrid)

		FIS1	PIGP
Description		fission, mitochondrial 1	phosphatidylinositol glycan anchor biosynthesis class P
Image			No pdb structure
GO Annotations	Cellular Component	Mitochondrion Peroxisome Integral Component Of Peroxisomal Membrane Endoplasmic Reticulum Membrane Integral Component Of Mitochondrial Outer Membrane Protein-containing Complex	Glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) Complex Endoplasmic Reticulum Membrane Integral Component Of Membrane
	Molecular Function	Protein Binding Identical Protein Binding	Protein Binding Phosphatidylinositol N-acetylglucosaminyltransferase Activity
	Biological Process	Mitochondrial Fission Autophagy Of Mitochondrion Release Of Cytochrome C From Mitochondria Protein Targeting To Mitochondrion Positive Regulation Of Cytosolic Calcium Ion Concentration Mitochondrial Fusion Regulation Of Mitochondrion Organization Peroxisome Fission Negative Regulation Of Endoplasmic Reticulum Calcium Ion Concentration Calcium-mediated Signaling Using Intracellular Calcium Source Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Mitochondrial Fragmentation Involved In Apoptotic Process Positive Regulation Of Mitochondrial Calcium Ion Concentration Mitochondrion Morphogenesis Positive Regulation Of Mitochondrial Fission Positive Regulation Of Protein Targeting To Membrane Negative Regulation Of ATP Metabolic Process Negative Regulation Of Fatty Acid Transport Positive Regulation Of Intrinsic Apoptotic Signaling Pathway	GPI Anchor Biosynthetic Process Preassembly Of GPI Anchor In ER Membrane
Pathways		Class I peroxisomal membrane protein import	Synthesis of glycosylphosphatidylinositol (GPI)
Drugs
Diseases
GWAS		Rheumatoid arthritis ( 30891314)
Interacting Genes		30 interacting genes: A2M ABHD6 APH1A BCAP31 CREB3 DNM1L EBP ERGIC3 FAM209A FAM210B FFAR2 JAGN1 KASH5 KCNJ6 MARCHF5 MMGT1 NOS3 PIGP RNASEK SCN3B SLC10A6 SLC14A1 SLC22A1 SLC22A2 SPCS1 TBC1D15 TMEM14B TMPPE UBC VKORC1	17 interacting genes: C1GALT1 DHRSX FIS1 IER3IP1 ITGAM LHFPL3 NINJ2 PLP1 PLP2 PTPN1 SCAMP5 SMAGP THSD7B TMEM107 TMEM19 TMEM229B UBIAD1
Entrez ID		51024	51227
HPRD ID		12352	05806
Ensembl ID		ENSG00000214253	ENSG00000185808
Uniprot IDs		Q9Y3D6	P57054
PDB IDs		1NZN 1PC2
Enriched GO Terms of Interacting Partners?
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