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FIS1 and MMGT1
Data Source:
BioGRID
(two hybrid)
FIS1
MMGT1
Description
fission, mitochondrial 1
membrane magnesium transporter 1
Image
GO Annotations
Cellular Component
Mitochondrion
Peroxisome
Integral Component Of Peroxisomal Membrane
Endoplasmic Reticulum
Membrane
Integral Component Of Mitochondrial Outer Membrane
Protein-containing Complex
Golgi Membrane
Early Endosome
Golgi Apparatus
Plasma Membrane
Membrane
Integral Component Of Membrane
Integral Component Of Endoplasmic Reticulum Membrane
Early Endosome Membrane
EMC Complex
Molecular Function
Protein Binding
Identical Protein Binding
Protein Binding
Cobalt Ion Transmembrane Transporter Activity
Ferrous Iron Transmembrane Transporter Activity
Magnesium Ion Transmembrane Transporter Activity
Inorganic Cation Transmembrane Transporter Activity
Membrane Insertase Activity
Biological Process
Mitochondrial Fission
Autophagy Of Mitochondrion
Release Of Cytochrome C From Mitochondria
Protein Targeting To Mitochondrion
Positive Regulation Of Cytosolic Calcium Ion Concentration
Mitochondrial Fusion
Regulation Of Mitochondrion Organization
Peroxisome Fission
Negative Regulation Of Endoplasmic Reticulum Calcium Ion Concentration
Calcium-mediated Signaling Using Intracellular Calcium Source
Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Mitochondrial Fragmentation Involved In Apoptotic Process
Positive Regulation Of Mitochondrial Calcium Ion Concentration
Mitochondrion Morphogenesis
Positive Regulation Of Mitochondrial Fission
Positive Regulation Of Protein Targeting To Membrane
Negative Regulation Of ATP Metabolic Process
Negative Regulation Of Fatty Acid Transport
Positive Regulation Of Intrinsic Apoptotic Signaling Pathway
Cobalt Ion Transport
Copper Ion Transport
Magnesium Ion Transport
Iron Ion Transmembrane Transport
Protein Insertion Into ER Membrane By Stop-transfer Membrane-anchor Sequence
Tail-anchored Membrane Protein Insertion Into ER Membrane
Magnesium Ion Transmembrane Transport
Pathways
Class I peroxisomal membrane protein import
Miscellaneous transport and binding events
Drugs
Diseases
GWAS
Rheumatoid arthritis (
30891314
)
Interacting Genes
30 interacting genes:
A2M
ABHD6
APH1A
BCAP31
CREB3
DNM1L
EBP
ERGIC3
FAM209A
FAM210B
FFAR2
JAGN1
KASH5
KCNJ6
MARCHF5
MMGT1
NOS3
PIGP
RNASEK
SCN3B
SLC10A6
SLC14A1
SLC22A1
SLC22A2
SPCS1
TBC1D15
TMEM14B
TMPPE
UBC
VKORC1
51 interacting genes:
ADGRE2
AGR3
ANKRD46
APP
C4orf3
C5
C8A
DEFB127
EMD
FIS1
FXYD6
GPR25
GRM2
INSIG2
ITGAM
LNPEP
MFF
MFSD3
MFSD5
MS4A13
NDUFA3
NINJ2
ORMDL2
PEX16
PLPP6
RUSF1
SEC22B
SLC35B4
SLC35E4
SLC38A7
SLC7A14
STX12
STX1A
STX1B
STX3
STX6
STX8
TAS2R19
TECR
THBD
TMBIM6
TMED8
TMEM14A
TMEM14C
TMEM229B
TMEM254
TMEM42
TMEM60
TMEM86B
VRK2
YIF1A
Entrez ID
51024
93380
HPRD ID
12352
06626
Ensembl ID
ENSG00000214253
ENSG00000169446
Uniprot IDs
Q9Y3D6
Q8N4V1
PDB IDs
1NZN
1PC2
6WW7
6Z3W
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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