FIS1 and TBC1D15

Data Source:
BioGRID (proximity labelling technology, affinity chromatography technology, pull down)

		FIS1	TBC1D15
Description		fission, mitochondrial 1	TBC1 domain family member 15
Image			No pdb structure
GO Annotations	Cellular Component	Mitochondrion Peroxisome Integral Component Of Peroxisomal Membrane Endoplasmic Reticulum Membrane Integral Component Of Mitochondrial Outer Membrane Protein-containing Complex	Extracellular Region Cytoplasm
	Molecular Function	Protein Binding Identical Protein Binding	GTPase Activator Activity Protein Binding
	Biological Process	Mitochondrial Fission Autophagy Of Mitochondrion Release Of Cytochrome C From Mitochondria Protein Targeting To Mitochondrion Positive Regulation Of Cytosolic Calcium Ion Concentration Mitochondrial Fusion Regulation Of Mitochondrion Organization Peroxisome Fission Negative Regulation Of Endoplasmic Reticulum Calcium Ion Concentration Calcium-mediated Signaling Using Intracellular Calcium Source Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Mitochondrial Fragmentation Involved In Apoptotic Process Positive Regulation Of Mitochondrial Calcium Ion Concentration Mitochondrion Morphogenesis Positive Regulation Of Mitochondrial Fission Positive Regulation Of Protein Targeting To Membrane Negative Regulation Of ATP Metabolic Process Negative Regulation Of Fatty Acid Transport Positive Regulation Of Intrinsic Apoptotic Signaling Pathway	Intracellular Protein Transport Regulation Of GTPase Activity Activation Of GTPase Activity Regulation Of Cilium Assembly
Pathways		Class I peroxisomal membrane protein import	TBC/RABGAPs
Drugs
Diseases
GWAS		Rheumatoid arthritis ( 30891314)	Inferior parietal cortex volume ( 31530798) Metabolite levels ( 23823483)
Interacting Genes		30 interacting genes: A2M ABHD6 APH1A BCAP31 CREB3 DNM1L EBP ERGIC3 FAM209A FAM210B FFAR2 JAGN1 KASH5 KCNJ6 MARCHF5 MMGT1 NOS3 PIGP RNASEK SCN3B SLC10A6 SLC14A1 SLC22A1 SLC22A2 SPCS1 TBC1D15 TMEM14B TMPPE UBC VKORC1	9 interacting genes: CALCOCO1 CEP63 FIS1 OPTN RAB5A RAB5B RAB5C TAX1BP1 UBC
Entrez ID		51024	64786
HPRD ID		12352	15470
Ensembl ID		ENSG00000214253	ENSG00000121749
Uniprot IDs		Q9Y3D6	A8K8E1 Q8TC07
PDB IDs		1NZN 1PC2
Enriched GO Terms of Interacting Partners?
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