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FIS1 and ABHD6
Data Source:
BioGRID
(two hybrid)
FIS1
ABHD6
Description
fission, mitochondrial 1
abhydrolase domain containing 6, acylglycerol lipase
Image
No pdb structure
GO Annotations
Cellular Component
Mitochondrion
Peroxisome
Integral Component Of Peroxisomal Membrane
Endoplasmic Reticulum
Membrane
Integral Component Of Mitochondrial Outer Membrane
Protein-containing Complex
Mitochondrion
Lysosomal Membrane
Plasma Membrane
Integral Component Of Membrane
Late Endosome Membrane
Mitochondrial Membrane
AMPA Glutamate Receptor Complex
Glutamatergic Synapse
GABA-ergic Synapse
Integral Component Of Postsynaptic Membrane
Molecular Function
Protein Binding
Identical Protein Binding
Phospholipase Activity
Protein Binding
Acylglycerol Lipase Activity
Biological Process
Mitochondrial Fission
Autophagy Of Mitochondrion
Release Of Cytochrome C From Mitochondria
Protein Targeting To Mitochondrion
Positive Regulation Of Cytosolic Calcium Ion Concentration
Mitochondrial Fusion
Regulation Of Mitochondrion Organization
Peroxisome Fission
Negative Regulation Of Endoplasmic Reticulum Calcium Ion Concentration
Calcium-mediated Signaling Using Intracellular Calcium Source
Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Mitochondrial Fragmentation Involved In Apoptotic Process
Positive Regulation Of Mitochondrial Calcium Ion Concentration
Mitochondrion Morphogenesis
Positive Regulation Of Mitochondrial Fission
Positive Regulation Of Protein Targeting To Membrane
Negative Regulation Of ATP Metabolic Process
Negative Regulation Of Fatty Acid Transport
Positive Regulation Of Intrinsic Apoptotic Signaling Pathway
Phospholipid Catabolic Process
Negative Regulation Of Cell Migration
Acylglycerol Catabolic Process
Positive Regulation Of Lipid Biosynthetic Process
Monoacylglycerol Catabolic Process
Long-term Synaptic Depression
Negative Regulation Of Cold-induced Thermogenesis
Regulation Of Endocannabinoid Signaling Pathway
Lysobisphosphatidic Acid Metabolic Process
Pathways
Class I peroxisomal membrane protein import
Arachidonate production from DAG
Drugs
Diseases
GWAS
Rheumatoid arthritis (
30891314
)
Hemoglobin levels (
32327693
)
Platelet count (
27863252
)
Refractive error (
32231278
)
Rheumatoid arthritis (
30423114
24390342
)
Systemic lupus erythematosus (
27399966
26502338
)
Interacting Genes
30 interacting genes:
A2M
ABHD6
APH1A
BCAP31
CREB3
DNM1L
EBP
ERGIC3
FAM209A
FAM210B
FFAR2
JAGN1
KASH5
KCNJ6
MARCHF5
MMGT1
NOS3
PIGP
RNASEK
SCN3B
SLC10A6
SLC14A1
SLC22A1
SLC22A2
SPCS1
TBC1D15
TMEM14B
TMPPE
UBC
VKORC1
6 interacting genes:
CKMT2
FIS1
PCGF2
RTP2
SCAMP4
TVP23B
Entrez ID
51024
57406
HPRD ID
12352
12407
Ensembl ID
ENSG00000214253
ENSG00000163686
Uniprot IDs
Q9Y3D6
A0A024R323
Q9BV23
PDB IDs
1NZN
1PC2
Enriched GO Terms of Interacting Partners
?
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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