POLR1E and NFKBIB

Data Source:
BioGRID (affinity chromatography technology, affinity chromatography technology)
HPRD (in vitro)

		POLR1E	NFKBIB
Description		RNA polymerase I subunit E	NFKB inhibitor beta
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Fibrillar Center Nucleoplasm Nucleolus RNA Polymerase I Complex	Nucleus Cytosol
	Molecular Function	RNA Polymerase I General Transcription Initiation Factor Binding DNA Binding DNA-directed 5'-3' RNA Polymerase Activity Protein Binding	Transcription Coactivator Activity Protein Binding
	Biological Process	RNA Polymerase I Preinitiation Complex Assembly Transcription Initiation From RNA Polymerase I Promoter Transcription Elongation From RNA Polymerase I Promoter Termination Of RNA Polymerase I Transcription Nucleolar Large RRNA Transcription By RNA Polymerase I Positive Regulation Of Gene Expression, Epigenetic	Transcription, DNA-templated Signal Transduction Cytoplasmic Sequestering Of NF-kappaB Positive Regulation Of Transcription, DNA-templated Cellular Response To Lipopolysaccharide
Pathways		NoRC negatively regulates rRNA expression B-WICH complex positively regulates rRNA expression RNA Polymerase I Transcription Initiation RNA Polymerase I Transcription Initiation RNA Polymerase I Promoter Escape RNA Polymerase I Transcription Termination	Activation of NF-kappaB in B cells RIP-mediated NFkB activation via ZBP1 TAK1 activates NFkB by phosphorylation and activation of IKKs complex TRAF6 mediated NF-kB activation
Drugs
Diseases
GWAS
Interacting Genes		8 interacting genes: NFKBIB POLR1A POLR1B POLR1C POLR1G SIRT7 TAF1C UBTF	43 interacting genes: APP BAK1 BTBD6 BTRC CDC25A CHUK CSNK2A1 CUL1 DNAJA3 ESR2 FHL3 GIT2 IKBKB IKBKG KPNA2 LRPPRC MCC MTIF2 NCOR2 NDUFB7 NFKB1 NFKB2 NFKBIA NGFR NKIRAS1 NKIRAS2 PDCD2 POLR1A POLR1B POLR1C POLR1D POLR1E POLR1G POLR2H POLR2L PPARG RASAL2 REL RELA RXRA SKP1 TSPAN1 VPS52
Entrez ID		64425	4793
HPRD ID		15096	07260
Ensembl ID		ENSG00000137054	ENSG00000104825
Uniprot IDs		B4E005 Q9GZS1	G5E9C2 Q15653
PDB IDs
Enriched GO Terms of Interacting Partners?
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