STAC and LIMD1

Data Source:
BioGRID (two hybrid)

		STAC	LIMD1
Description		SH3 and cysteine rich domain	LIM domain containing 1
Image			No pdb structure
GO Annotations	Cellular Component	Cytosol T-tubule Extrinsic Component Of Cytoplasmic Side Of Plasma Membrane	P-body Nucleus Nucleoplasm Transcription Regulator Complex Cytoplasm Cytosol Plasma Membrane Adherens Junction Focal Adhesion RISC Complex
	Molecular Function	Protein Binding Ion Channel Binding Metal Ion Binding	Transcription Corepressor Activity Protein Binding Metal Ion Binding
	Biological Process	Skeletal Muscle Contraction Signal Transduction Cellular Response To Heat Intracellular Signal Transduction Positive Regulation Of Voltage-gated Calcium Channel Activity Positive Regulation Of Protein Localization To Plasma Membrane Positive Regulation Of Cation Channel Activity	Response To Hypoxia Osteoblast Development Regulation Of Transcription, DNA-templated Cytoskeleton Organization Regulation Of Cell Shape Phosphorylation Cell Migration P-body Assembly Gene Silencing By MiRNA Negative Regulation Of Hippo Signaling Negative Regulation Of Osteoblast Differentiation Negative Regulation Of Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Negative Regulation Of Canonical Wnt Signaling Pathway Positive Regulation Of Gene Silencing By MiRNA
Pathways			Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha
Drugs
Diseases
GWAS		Age-related cognitive decline (global cognition) (slope of z-scores) ( 30954325) Age-related cognitive decline (language) (slope of z-scores) ( 30954325) Arterial stiffness (brachial-femoral pulse wave velocity) ( 32790701) Asthma ( 29273806) Brooding (response to stress) ( 30886212) Celiac disease ( 23936387) Erectile dysfunction in type 1 diabetes ( 22704111) Itch intensity from mosquito bite adjusted by bite size ( 28199695) Kidney disease (end stage renal disease vs non-end stage renal disease) in type 1 diabetes ( 31537649) Metabolite levels ( 23823483) Smoking behaviour (maximum cigarettes in a 24 hour period) ( 29532581)	Acne (severe) ( 24927181) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545) Systolic blood pressure ( 30578418)
Interacting Genes		22 interacting genes: APP FBXO25 GOLGA2 KANK2 KIAA1958 LIMD1 LMNA LRRK2 LZTS2 MEOX2 NBPF19 NCKIPSD NEDD4L NOTCH2NLA PAX5 PAX6 PJA1 POU6F2 RNF208 STAT5B TRIP6 TRMO	6 interacting genes: APP BRCA2 HIPK3 RPP14 STAC TRAF6
Entrez ID		6769	8994
HPRD ID		11890	05177
Ensembl ID		ENSG00000144681	ENSG00000144791
Uniprot IDs		B4DR96 B4DZ13 E9PEA7 Q8WUK8 Q99469	Q9UGP4
PDB IDs		2DL4 6B25
Enriched GO Terms of Interacting Partners?
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