STAC and RNF208

Data Source:
BioGRID (two hybrid)

		STAC	RNF208
Description		SH3 and cysteine rich domain	ring finger protein 208
Image			No pdb structure
GO Annotations	Cellular Component	Cytosol T-tubule Extrinsic Component Of Cytoplasmic Side Of Plasma Membrane	Nucleoplasm Cytosol
	Molecular Function	Protein Binding Ion Channel Binding Metal Ion Binding	Ubiquitin-protein Transferase Activity Protein Binding Metal Ion Binding
	Biological Process	Skeletal Muscle Contraction Signal Transduction Cellular Response To Heat Intracellular Signal Transduction Positive Regulation Of Voltage-gated Calcium Channel Activity Positive Regulation Of Protein Localization To Plasma Membrane Positive Regulation Of Cation Channel Activity	Protein Autoubiquitination
Pathways
Drugs
Diseases
GWAS		Age-related cognitive decline (global cognition) (slope of z-scores) ( 30954325) Age-related cognitive decline (language) (slope of z-scores) ( 30954325) Arterial stiffness (brachial-femoral pulse wave velocity) ( 32790701) Asthma ( 29273806) Brooding (response to stress) ( 30886212) Celiac disease ( 23936387) Erectile dysfunction in type 1 diabetes ( 22704111) Itch intensity from mosquito bite adjusted by bite size ( 28199695) Kidney disease (end stage renal disease vs non-end stage renal disease) in type 1 diabetes ( 31537649) Metabolite levels ( 23823483) Smoking behaviour (maximum cigarettes in a 24 hour period) ( 29532581)
Interacting Genes		22 interacting genes: APP FBXO25 GOLGA2 KANK2 KIAA1958 LIMD1 LMNA LRRK2 LZTS2 MEOX2 NBPF19 NCKIPSD NEDD4L NOTCH2NLA PAX5 PAX6 PJA1 POU6F2 RNF208 STAT5B TRIP6 TRMO	18 interacting genes: BUD31 CREB5 DAZAP2 GRB2 HOXA1 KRTAP15-1 KRTAP26-1 LITAF OXER1 PIN1 RNF38 RPIA SH3RF1 STAC TRIM32 UBQLN1 UBQLN2 USP54
Entrez ID		6769	727800
HPRD ID		11890
Ensembl ID		ENSG00000144681	ENSG00000212864
Uniprot IDs		B4DR96 B4DZ13 E9PEA7 Q8WUK8 Q99469	Q9H0X6
PDB IDs		2DL4 6B25
Enriched GO Terms of Interacting Partners?
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