KIF22 and PJA1

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		KIF22	PJA1
Description		kinesin family member 22	praja ring finger ubiquitin ligase 1
Image
GO Annotations	Cellular Component	Kinetochore Chromatin Nucleus Cytosol Kinesin Complex Microtubule Nuclear Speck Mitotic Spindle	Cytoplasm
	Molecular Function	DNA Binding Microtubule Motor Activity Protein Binding ATP Binding Microtubule Binding ATPase Activity	Protein Binding Metal Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process	Mitotic Cell Cycle DNA Repair Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Microtubule-based Movement Sister Chromatid Cohesion Mitotic Metaphase Plate Congression Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Metaphase Plate Congression	Protein Ubiquitination Protein Catabolic Process
Pathways		MHC class II antigen presentation COPI-dependent Golgi-to-ER retrograde traffic Kinesins	Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Red blood cell traits ( 23222517)	Birth weight ( 31043758) Body mass index ( 29273807) Platelet count ( 32888494) Plateletcrit ( 32888494) Schizophrenia ( 25056061 29483656)
Interacting Genes		6 interacting genes: ATXN1 GDF9 IMMT PJA1 SIAH1 SVIL	64 interacting genes: ABR ASCC2 ATP5F1C ATXN3 ATXN3L CAMK1G CDK16 COASY CSAG3 DDX54 EED ELAC1 ESPL1 EZH2 FGF12 GATD3A GLO1 GSR GTF2I HNRNPC HNRNPL HOMER2 JOSD1 KIF22 LCP2 LRG1 MAGEB4 MAGED1 MDM2 METAP2 NAGK NATD1 NDN OTUB1 OTUB2 PCCA PFKFB4 PHGDH PIP4K2C RIBC2 SPTBN1 STAC STAM STAMBP SUZ12 TAF9 TK1 TMEM214 TSSK3 TXNDC5 UBE2D2 UBE2D3 UBE2E3 UBE2K UBE2L3 UBE2U UCHL3 UCHL5 USP20 USP28 USP5 USP51 USP8 ZNF440
Entrez ID		3835	64219
HPRD ID		04445	02335
Ensembl ID		ENSG00000079616	ENSG00000181191
Uniprot IDs		A0A024R632 B7Z9T5 Q14807	Q8NG27
PDB IDs		2EDU 6NJE	2L0B
Enriched GO Terms of Interacting Partners?
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