KIF22 and GDF9

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		KIF22	GDF9
Description		kinesin family member 22	growth differentiation factor 9
Image			No pdb structure
GO Annotations	Cellular Component	Kinetochore Chromatin Nucleus Cytosol Kinesin Complex Microtubule Nuclear Speck Mitotic Spindle	Extracellular Space Cytoplasm
	Molecular Function	DNA Binding Microtubule Motor Activity Protein Binding ATP Binding Microtubule Binding ATPase Activity	Cytokine Activity Growth Factor Activity Type I Activin Receptor Binding
	Biological Process	Mitotic Cell Cycle DNA Repair Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Microtubule-based Movement Sister Chromatid Cohesion Mitotic Metaphase Plate Congression Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Metaphase Plate Congression	Oocyte Growth Transforming Growth Factor Beta Receptor Signaling Pathway Female Gamete Generation Positive Regulation Of Cell Population Proliferation Positive Regulation Of Pathway-restricted SMAD Protein Phosphorylation Negative Regulation Of Cell Growth BMP Signaling Pathway SMAD Protein Signal Transduction Regulation Of Progesterone Secretion
Pathways		MHC class II antigen presentation COPI-dependent Golgi-to-ER retrograde traffic Kinesins
Drugs
Diseases
GWAS		Red blood cell traits ( 23222517)	Asthma ( 31619474)
Interacting Genes		6 interacting genes: ATXN1 GDF9 IMMT PJA1 SIAH1 SVIL	45 interacting genes: ACVR2A ADPGK ANXA7 APLP1 BMP15 BMPR1A BMPR1B BMPR2 BTBD2 CDKN1A CDKN2C CRELD1 DLEU1 DNM2 FOXG1 FXYD6 GADD45G ILF3 KDM1A KIF22 LSM3 MOB4 MPHOSPH6 MYCBP NDUFB9 ORAI2 PABPC4 PAFAH1B3 PCDHA4 PCYT2 PMF1 PRKRA PSMD11 RAB27A RSRC1 S100A8 SAT1 SERPINB9 SMN1 SNRPG STRN4 TDGF1 TK1 TRIB3 WASHC3
Entrez ID		3835	2661
HPRD ID		04445	03560
Ensembl ID		ENSG00000079616	ENSG00000164404
Uniprot IDs		A0A024R632 B7Z9T5 Q14807	B4DXG3 O60383
PDB IDs		2EDU 6NJE
Enriched GO Terms of Interacting Partners?
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