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MAPK6 and EMD
Data Source:
BioGRID
(two hybrid)
MAPK6
EMD
Description
mitogen-activated protein kinase 6
emerin
Image
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
Cytoplasm
Cytosol
Nuclear Envelope
Nuclear Inner Membrane
Nuclear Outer Membrane
Nucleoplasm
Cytoplasm
Endoplasmic Reticulum
Spindle
Microtubule
Membrane
Integral Component Of Membrane
Spindle Pole Centrosome
Nuclear Membrane
Cortical Endoplasmic Reticulum
Molecular Function
Protein Serine/threonine Kinase Activity
MAP Kinase Activity
Protein Binding
ATP Binding
Actin Binding
Protein Binding
Cadherin Binding
Beta-tubulin Binding
Biological Process
MAPK Cascade
Protein Phosphorylation
Cell Cycle
Signal Transduction
Intracellular Signal Transduction
Muscle Contraction
Mitotic Nuclear Envelope Reassembly
Muscle Organ Development
Skeletal Muscle Cell Differentiation
Positive Regulation Of Protein Export From Nucleus
Negative Regulation Of Fibroblast Proliferation
Regulation Of Canonical Wnt Signaling Pathway
Cellular Response To Growth Factor Stimulus
Nuclear Membrane Organization
Negative Regulation Of Canonical Wnt Signaling Pathway
Pathways
MAPK6/MAPK4 signaling
Nuclear Envelope Breakdown
Initiation of Nuclear Envelope (NE) Reformation
Depolymerisation of the Nuclear Lamina
Insertion of tail-anchored proteins into the endoplasmic reticulum membrane
Insertion of tail-anchored proteins into the endoplasmic reticulum membrane
Drugs
Acetylsalicylic acid
Minocycline
Diseases
Emery-Dreifuss muscular dystrophy
GWAS
Serum uric acid levels in response to allopurinol in gout (
25676789
)
Mean spheric corpuscular volume (
32888494
)
Interacting Genes
166 interacting genes:
ACTG1
ACTR1B
AMPH
ANAPC5
ANK3
ANKRD2
APBA2
ARHGDIA
ARPC3
ATG9A
ATP5PF
BAG6
BARX1
BBS10
CA1
CA12
CALR
CASP6
CCND3
CCT3
CDH13
CERS1
CFAP298
CFL1
CNTN1
CNTRL
COPS6
CSE1L
CYRIB
CYTH2
DBN1
DCTN2
DDOST
DDR1
DGKZ
DKC1
DNAJC28
DPPA4
DST
DYNC2I2
EDF1
EEF1A2
EIF1
EIF3C
EIF4A1
ELOF1
EMD
FBXL16
FOXO3
FXYD3
GALNT7
GATA1
GLRX3
GORASP1
GPX1
HACL1
HAUS2
HDAC11
HIP1
HNRNPA0
HNRNPD
HNRNPH3
HSP90AB1
HSP90B1
HSPD1
IDH3B
INS
ITGB3BP
ITSN1
JUNB
KDSR
KLC1
KNSTRN
LPXN
MAP3K12
MAP3K7
MAPKAPK5
MASP1
MBIP
MBOAT7
MCM3
MDK
METTL17
METTL2A
MGAT1
MIPEP
MOK
MON1A
MTG2
MYBL2
MYOZ3
MZB1
NAT9
NAXE
NDUFS6
NECTIN2
NELFB
NOL4
NRXN2
NUDT5
OSTF1
PDCD6IP
PDLIM1
PHACTR3
PHC2
PHGDH
PIH1D1
PLEKHM1
PLSCR1
PPBP
PPP1R7
PPP2R1A
PRKAB1
PRKAR1A
PRKCB
PRPF38A
PSAT1
PSIP1
PTPMT1
RAB2A
RAB31
RACK1
RANBP9
RAP1GAP
RARA
RBL1
RGS19
RPL10
RRP7A
SEPTIN3
SEPTIN5
SERPINA4
SHC1
SLC20A1
SLC41A3
SMAD6
SMS
SNAPC4
SNW1
SOCS3
SPG7
SPRR2D
SPTAN1
SRSF5
STX7
TDP2
THAP4
TPI1
TTK
TUBA1A
UBA52
UBE2L3
URB1
USP20
VPS26C
WDR26
WFS1
WWC1
XPO1
ZNF133
ZNF205
ZNF331
ZNF579
ZNF600
ZNF671
ZNF775
98 interacting genes:
ABL1
ABT1
ACTB
ACTG2
AEN
AKAP8L
ANK1
ANKS6
AVPI1
BANF1
BCLAF1
BEND7
BYSL
CATSPER1
CCDC33
CCNL2
CD33
CEP70
CERS4
CISD2
CLEC14A
COMT
COPS6
CPLX4
CREB3
CTNNBIP1
CXorf66
DPPA4
EFHC2
ERMAP
FAM209A
FATE1
GMCL1
GOLM2
GORAB
GPR152
GRAMD2A
HSF2BP
INCA1
KASH5
KCNJ12
KCNJ18
KCNJ8
KCNN3
KIF9
KIR2DL3
LIME1
LMNA
LMO7
LPL
LUZP4
MAB21L3
MAPK6
MEOX1
MEOX2
MMGT1
MRPL45
MTERF4
MTNR1A
NCAPH2
NF2
NPDC1
PAK5
PIMREG
PSME1
REL
RNASEH1
RNF123
SH3GL2
SH3GL3
SOWAHB
SRC
SSMEM1
STX1A
STX4
SYNE1
TCF23
TMEM174
TMEM200A
TMEM201
TMEM52B
TMEM80
TMX2
TRAF3IP3
TRIM42
VAPB
VAV1
YTHDC1
ZFP1
ZFP57
ZFP64
ZNF165
ZNF232
ZNF329
ZNF341
ZNF398
ZNF549
ZNF774
Entrez ID
5597
2010
HPRD ID
04213
02309
Ensembl ID
ENSG00000069956
ENSG00000102119
Uniprot IDs
Q16659
P50402
PDB IDs
6YKY
6YLC
6YLL
7AQB
1JEI
2ODC
2ODG
6GHD
6RPR
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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