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MAPK6 and JUNB
Data Source:
BioGRID
(two hybrid)
MAPK6
JUNB
Description
mitogen-activated protein kinase 6
JunB proto-oncogene, AP-1 transcription factor subunit
Image
No pdb structure
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
Cytoplasm
Cytosol
Chromatin
Nucleoplasm
Transcription Regulator Complex
Transcription Factor AP-1 Complex
Molecular Function
Protein Serine/threonine Kinase Activity
MAP Kinase Activity
Protein Binding
ATP Binding
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
DNA-binding Transcription Activator Activity, RNA Polymerase II-specific
DNA Binding
Protein Binding
Transcription Factor Binding
Sequence-specific Double-stranded DNA Binding
Biological Process
MAPK Cascade
Protein Phosphorylation
Cell Cycle
Signal Transduction
Intracellular Signal Transduction
Vasculogenesis
Osteoblast Differentiation
Trophectodermal Cell Differentiation
Regulation Of Transcription By RNA Polymerase II
Cytokine-mediated Signaling Pathway
Osteoclast Differentiation
Osteoblast Proliferation
Regulation Of Cell Population Proliferation
Positive Regulation Of Cell Differentiation
Positive Regulation Of Transcription By RNA Polymerase II
Decidualization
Regulation Of Cell Cycle
Embryonic Process Involved In Female Pregnancy
Labyrinthine Layer Blood Vessel Development
Cellular Response To Calcium Ion
Pathways
MAPK6/MAPK4 signaling
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
Interleukin-4 and Interleukin-13 signaling
NGF-stimulated transcription
NGF-stimulated transcription
Drugs
Acetylsalicylic acid
Minocycline
Diseases
GWAS
Serum uric acid levels in response to allopurinol in gout (
25676789
)
Interacting Genes
166 interacting genes:
ACTG1
ACTR1B
AMPH
ANAPC5
ANK3
ANKRD2
APBA2
ARHGDIA
ARPC3
ATG9A
ATP5PF
BAG6
BARX1
BBS10
CA1
CA12
CALR
CASP6
CCND3
CCT3
CDH13
CERS1
CFAP298
CFL1
CNTN1
CNTRL
COPS6
CSE1L
CYRIB
CYTH2
DBN1
DCTN2
DDOST
DDR1
DGKZ
DKC1
DNAJC28
DPPA4
DST
DYNC2I2
EDF1
EEF1A2
EIF1
EIF3C
EIF4A1
ELOF1
EMD
FBXL16
FOXO3
FXYD3
GALNT7
GATA1
GLRX3
GORASP1
GPX1
HACL1
HAUS2
HDAC11
HIP1
HNRNPA0
HNRNPD
HNRNPH3
HSP90AB1
HSP90B1
HSPD1
IDH3B
INS
ITGB3BP
ITSN1
JUNB
KDSR
KLC1
KNSTRN
LPXN
MAP3K12
MAP3K7
MAPKAPK5
MASP1
MBIP
MBOAT7
MCM3
MDK
METTL17
METTL2A
MGAT1
MIPEP
MOK
MON1A
MTG2
MYBL2
MYOZ3
MZB1
NAT9
NAXE
NDUFS6
NECTIN2
NELFB
NOL4
NRXN2
NUDT5
OSTF1
PDCD6IP
PDLIM1
PHACTR3
PHC2
PHGDH
PIH1D1
PLEKHM1
PLSCR1
PPBP
PPP1R7
PPP2R1A
PRKAB1
PRKAR1A
PRKCB
PRPF38A
PSAT1
PSIP1
PTPMT1
RAB2A
RAB31
RACK1
RANBP9
RAP1GAP
RARA
RBL1
RGS19
RPL10
RRP7A
SEPTIN3
SEPTIN5
SERPINA4
SHC1
SLC20A1
SLC41A3
SMAD6
SMS
SNAPC4
SNW1
SOCS3
SPG7
SPRR2D
SPTAN1
SRSF5
STX7
TDP2
THAP4
TPI1
TTK
TUBA1A
UBA52
UBE2L3
URB1
USP20
VPS26C
WDR26
WFS1
WWC1
XPO1
ZNF133
ZNF205
ZNF331
ZNF579
ZNF600
ZNF671
ZNF775
39 interacting genes:
APLP2
ATF4
BATF
BATF2
BCL6
BDNF
BRCA1
DDIT3
DNMT3L
EP300
ESR1
FOS
FOSB
FOSL1
FOSL2
HOXA7
ITCH
JDP2
MAP2
MAPK14
MAPK6
MAPK8
MAPK9
NEU1
NFE2L1
NINL
PKIA
SAT1
SET
SMAD3
SMAD4
SMURF1
TCERG1
TDG
UBA6
UBE2I
USP24
ZNF595
ZSWIM9
Entrez ID
5597
3726
HPRD ID
04213
01303
Ensembl ID
ENSG00000069956
ENSG00000171223
Uniprot IDs
Q16659
P17275
Q5U079
PDB IDs
6YKY
6YLC
6YLL
7AQB
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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