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MAPK6 and SERPINA4
Data Source:
BioGRID
(two hybrid)
MAPK6
SERPINA4
Description
mitogen-activated protein kinase 6
serpin family A member 4
Image
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
Cytoplasm
Cytosol
Extracellular Region
Extracellular Space
Platelet Dense Granule Lumen
Extracellular Exosome
Molecular Function
Protein Serine/threonine Kinase Activity
MAP Kinase Activity
Protein Binding
ATP Binding
Serine-type Endopeptidase Inhibitor Activity
Biological Process
MAPK Cascade
Protein Phosphorylation
Cell Cycle
Signal Transduction
Intracellular Signal Transduction
Platelet Degranulation
Negative Regulation Of Endopeptidase Activity
Pathways
MAPK6/MAPK4 signaling
Platelet degranulation
Drugs
Acetylsalicylic acid
Minocycline
Zinc
Copper
Zinc acetate
Diseases
GWAS
Serum uric acid levels in response to allopurinol in gout (
25676789
)
Blood protein levels (
30072576
29875488
28240269
)
Vaspin levels (
22907691
)
Interacting Genes
166 interacting genes:
ACTG1
ACTR1B
AMPH
ANAPC5
ANK3
ANKRD2
APBA2
ARHGDIA
ARPC3
ATG9A
ATP5PF
BAG6
BARX1
BBS10
CA1
CA12
CALR
CASP6
CCND3
CCT3
CDH13
CERS1
CFAP298
CFL1
CNTN1
CNTRL
COPS6
CSE1L
CYRIB
CYTH2
DBN1
DCTN2
DDOST
DDR1
DGKZ
DKC1
DNAJC28
DPPA4
DST
DYNC2I2
EDF1
EEF1A2
EIF1
EIF3C
EIF4A1
ELOF1
EMD
FBXL16
FOXO3
FXYD3
GALNT7
GATA1
GLRX3
GORASP1
GPX1
HACL1
HAUS2
HDAC11
HIP1
HNRNPA0
HNRNPD
HNRNPH3
HSP90AB1
HSP90B1
HSPD1
IDH3B
INS
ITGB3BP
ITSN1
JUNB
KDSR
KLC1
KNSTRN
LPXN
MAP3K12
MAP3K7
MAPKAPK5
MASP1
MBIP
MBOAT7
MCM3
MDK
METTL17
METTL2A
MGAT1
MIPEP
MOK
MON1A
MTG2
MYBL2
MYOZ3
MZB1
NAT9
NAXE
NDUFS6
NECTIN2
NELFB
NOL4
NRXN2
NUDT5
OSTF1
PDCD6IP
PDLIM1
PHACTR3
PHC2
PHGDH
PIH1D1
PLEKHM1
PLSCR1
PPBP
PPP1R7
PPP2R1A
PRKAB1
PRKAR1A
PRKCB
PRPF38A
PSAT1
PSIP1
PTPMT1
RAB2A
RAB31
RACK1
RANBP9
RAP1GAP
RARA
RBL1
RGS19
RPL10
RRP7A
SEPTIN3
SEPTIN5
SERPINA4
SHC1
SLC20A1
SLC41A3
SMAD6
SMS
SNAPC4
SNW1
SOCS3
SPG7
SPRR2D
SPTAN1
SRSF5
STX7
TDP2
THAP4
TPI1
TTK
TUBA1A
UBA52
UBE2L3
URB1
USP20
VPS26C
WDR26
WFS1
WWC1
XPO1
ZNF133
ZNF205
ZNF331
ZNF579
ZNF600
ZNF671
ZNF775
13 interacting genes:
CTSD
GADD45G
ILK
KLK1
KLK2
MAP4K2
MAPK6
NR4A1
RASA1
TAB1
TNFRSF14
TNNT1
YAE1
Entrez ID
5597
5267
HPRD ID
04213
01004
Ensembl ID
ENSG00000069956
ENSG00000100665
Uniprot IDs
Q16659
A0A024R6I9
P29622
PDB IDs
6YKY
6YLC
6YLL
7AQB
6F02
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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