PLEKHA5 and SH3BP5L

Data Source:
BioGRID (two hybrid)

		PLEKHA5	SH3BP5L
Description		pleckstrin homology domain containing A5	SH3 binding domain protein 5 like
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytosol Postsynaptic Density Membrane Glutamatergic Synapse	Cytoplasm
	Molecular Function	Protein Binding Phosphatidylinositol-5-phosphate Binding Phosphatidylinositol-3-phosphate Binding Phosphatidylinositol-4-phosphate Binding Phosphatidylinositol-3,5-bisphosphate Binding	Protein Kinase Inhibitor Activity Guanyl-nucleotide Exchange Factor Activity Protein Binding
	Biological Process	Biological_process Reproductive System Development	Intracellular Signal Transduction Negative Regulation Of Protein Tyrosine Kinase Activity
Pathways		Synthesis of PIPs at the plasma membrane
Drugs
Diseases
GWAS		Adult body size ( 32376654) Chronic mountain sickness ( 31417607) Daytime sleep phenotypes ( 27126917) Gut microbiota (bacterial taxa) ( 27694959) Gut microbiota (bacterial taxa, rank normal transformation method) ( 32572223) Pharmacokinetics of antiepileptic drugs in severe mental disorder (concentration drug ratio) ( 25944848) Platelet reactivity in response to clopidogrel treatment ( 32472697) Thalamus volume ( 31530798)	Lead levels ( 26025379)
Interacting Genes		31 interacting genes: ARHGEF9 BLOC1S6 CCDC186 CCDC88B CCDC92 CEP250 CEP350 DES EVPL EXTL3 KANSL1 KIF3A KRT19 KRT20 KTN1 LAMB2 LSM4 MAX PDZD11 PLEC PLEKHA6 PPP1R13B PROM1 SH3BP5L SOGA1 SPTAN1 SPTBN1 SRPK2 UPF1 WASH2P YWHAG	10 interacting genes: CEP57 EMC2 FAM161B NINL PLEKHA5 RAB11B RAB14 RAB25 SUOX YWHAG
Entrez ID		54477	80851
HPRD ID		09684	13887
Ensembl ID		ENSG00000052126	ENSG00000175137
Uniprot IDs		A0A024RAY7 Q9HAU0	A0A024R0T2 Q7L8J4
PDB IDs		2DKP
Enriched GO Terms of Interacting Partners?
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