SH3BP5L and RAB11B

Data Source:
BioGRID (two hybrid)

		SH3BP5L	RAB11B
Description		SH3 binding domain protein 5 like	RAB11B, member RAS oncogene family
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm	Endosome Cytosol Synaptic Vesicle Phagocytic Vesicle Membrane Phagocytic Vesicle Recycling Endosome Recycling Endosome Membrane Extracellular Exosome Anchored Component Of Synaptic Vesicle Membrane
	Molecular Function	Protein Kinase Inhibitor Activity Guanyl-nucleotide Exchange Factor Activity Protein Binding	GTPase Activity Protein Binding GTP Binding GDP Binding Myosin V Binding Cadherin Binding
	Biological Process	Intracellular Signal Transduction Negative Regulation Of Protein Tyrosine Kinase Activity	Receptor Recycling Exocytosis Melanosome Transport Transferrin Transport Insulin Secretion Involved In Cellular Response To Glucose Stimulus Post-translational Protein Modification Regulation Of Anion Transport Constitutive Secretory Pathway Regulated Exocytosis Cellular Response To Acidic PH Establishment Of Protein Localization To Membrane Amyloid-beta Clearance By Transcytosis Retrograde Transport, Endosome To Plasma Membrane Regulation Of Protein Localization To Cell Surface Regulation Of Endocytic Recycling
Pathways			TBC/RABGAPs RAB geranylgeranylation
Drugs
Diseases
GWAS		Lead levels ( 26025379)	High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Immature fraction of reticulocytes ( 32888494)
Interacting Genes		10 interacting genes: CEP57 EMC2 FAM161B NINL PLEKHA5 RAB11B RAB14 RAB25 SUOX YWHAG	11 interacting genes: APP IKBKG MEOX2 MYO5B OPTN RAB11FIP1 RAB11FIP2 RAB11FIP3 RAB11FIP5 SH3BP5L SREBF2
Entrez ID		80851	9230
HPRD ID		13887	05009
Ensembl ID		ENSG00000175137	ENSG00000185236
Uniprot IDs		A0A024R0T2 Q7L8J4	Q15907
PDB IDs			2F9L 2F9M 4OJK
Enriched GO Terms of Interacting Partners?
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