SH3BP5L and RAB25

		SH3BP5L	RAB25
Description		SH3 binding domain protein 5 like	RAB25, member RAS oncogene family
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm	Endosome Pseudopodium Pseudopodium Membrane Cytoplasmic Vesicle Recycling Endosome Extracellular Exosome
	Molecular Function	Protein Kinase Inhibitor Activity Guanyl-nucleotide Exchange Factor Activity Protein Binding	GTPase Activity Protein Binding GTP Binding Myosin V Binding
	Biological Process	Intracellular Signal Transduction Negative Regulation Of Protein Tyrosine Kinase Activity	Epithelial Cell Morphogenesis Exocytosis Positive Regulation Of Cell Population Proliferation Positive Regulation Of Epithelial Cell Migration Protein Transport Pseudopodium Organization Regulation Of Vesicle-mediated Transport
Pathways			RAB geranylgeranylation
Drugs
Diseases
GWAS		Lead levels ( 26025379)	Apolipoprotein A1 levels ( 32203549) HDL cholesterol levels ( 32203549) Parkinson's disease ( 32201043)
Interacting Genes		10 interacting genes: CEP57 EMC2 FAM161B NINL PLEKHA5 RAB11B RAB14 RAB25 SUOX YWHAG	14 interacting genes: ACVR1 BMPR1B ITGB1 MED31 MYO5B OPTN RAB11FIP1 RAB11FIP2 RAB11FIP3 RAB11FIP5 SH3BP5L SMAD4 SMURF2 TGFBR1
Entrez ID		80851	57111
HPRD ID		13887	06698
Ensembl ID		ENSG00000175137	ENSG00000132698
Uniprot IDs		A0A024R0T2 Q7L8J4	P57735
PDB IDs			2OIL 3TSO
Enriched GO Terms of Interacting Partners?
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