SH3BP5L and RAB14

Data Source:
BioGRID (two hybrid)

		SH3BP5L	RAB14
Description		SH3 binding domain protein 5 like	RAB14, member RAS oncogene family
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm	Golgi Membrane Lysosome Lysosomal Membrane Early Endosome Late Endosome Rough Endoplasmic Reticulum Golgi Stack Trans-Golgi Network Cytosol Plasma Membrane Cilium Endomembrane System Trans-Golgi Network Transport Vesicle Early Endosome Membrane Nuclear Outer Membrane-endoplasmic Reticulum Membrane Network Intracellular Membrane-bounded Organelle Phagocytic Vesicle Perinuclear Region Of Cytoplasm Recycling Endosome Recycling Endosome Membrane Extracellular Exosome Tertiary Granule Membrane
	Molecular Function	Protein Kinase Inhibitor Activity Guanyl-nucleotide Exchange Factor Activity Protein Binding	GTPase Activity Protein Binding GTP Binding GDP Binding Myosin V Binding
	Biological Process	Intracellular Signal Transduction Negative Regulation Of Protein Tyrosine Kinase Activity	Phosphatidylinositol Biosynthetic Process Intracellular Protein Transport Golgi To Endosome Transport Fibroblast Growth Factor Receptor Signaling Pathway Vesicle-mediated Transport Endocytic Recycling Regulation Of Protein Localization Defense Response To Bacterium Neutrophil Degranulation Regulation Of Embryonic Development Intracellular Transport Phagolysosome Assembly Involved In Apoptotic Cell Clearance
Pathways			Translocation of SLC2A4 (GLUT4) to the plasma membrane Synthesis of PIPs at the plasma membrane Neutrophil degranulation RAB geranylgeranylation RAB GEFs exchange GTP for GDP on RABs
Drugs
Diseases
GWAS		Lead levels ( 26025379)	Immune reponse to smallpox (secreted IFN-alpha) ( 22610502)
Interacting Genes		10 interacting genes: CEP57 EMC2 FAM161B NINL PLEKHA5 RAB11B RAB14 RAB25 SUOX YWHAG	12 interacting genes: ADRB2 APP CHM EXOC5 FAM71C OCRL OPTN RAB11FIP5 RBSN RUFY1 SH3BP5L SMURF2
Entrez ID		80851	51552
HPRD ID		13887	06693
Ensembl ID		ENSG00000175137	ENSG00000119396
Uniprot IDs		A0A024R0T2 Q7L8J4	A0A024R845 P61106
PDB IDs			1Z0F 4D0G 4DRZ
Enriched GO Terms of Interacting Partners?
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