PLEKHA5 and PDZD11

Data Source:
BioGRID (two hybrid)

		PLEKHA5	PDZD11
Description		pleckstrin homology domain containing A5	PDZ domain containing 11
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytosol Postsynaptic Density Membrane Glutamatergic Synapse	Extracellular Region Cytosol Cell-cell Junction Adherens Junction Basolateral Plasma Membrane Synapse Pore Complex Presynapse
	Molecular Function	Protein Binding Phosphatidylinositol-5-phosphate Binding Phosphatidylinositol-3-phosphate Binding Phosphatidylinositol-4-phosphate Binding Phosphatidylinositol-3,5-bisphosphate Binding	Protein Binding
	Biological Process	Biological_process Reproductive System Development	Biotin Metabolic Process Neurotransmitter Secretion Pantothenate Metabolic Process Antimicrobial Humoral Response Ion Transmembrane Transport Maintenance Of Epithelial Cell Apical/basal Polarity Pore Complex Assembly Transmembrane Transport Protein Localization To Basolateral Plasma Membrane
Pathways		Synthesis of PIPs at the plasma membrane	Biotin transport and metabolism Vitamin B5 (pantothenate) metabolism Transport of vitamins, nucleosides, and related molecules Ion influx/efflux at host-pathogen interface Ion transport by P-type ATPases
Drugs
Diseases
GWAS		Adult body size ( 32376654) Chronic mountain sickness ( 31417607) Daytime sleep phenotypes ( 27126917) Gut microbiota (bacterial taxa) ( 27694959) Gut microbiota (bacterial taxa, rank normal transformation method) ( 32572223) Pharmacokinetics of antiepileptic drugs in severe mental disorder (concentration drug ratio) ( 25944848) Platelet reactivity in response to clopidogrel treatment ( 32472697) Thalamus volume ( 31530798)
Interacting Genes		31 interacting genes: ARHGEF9 BLOC1S6 CCDC186 CCDC88B CCDC92 CEP250 CEP350 DES EVPL EXTL3 KANSL1 KIF3A KRT19 KRT20 KTN1 LAMB2 LSM4 MAX PDZD11 PLEC PLEKHA6 PPP1R13B PROM1 SH3BP5L SOGA1 SPTAN1 SPTBN1 SRPK2 UPF1 WASH2P YWHAG	5 interacting genes: ATP2B2 ATP7A MAGI2 PLEKHA5 SIGMAR1
Entrez ID		54477	51248
HPRD ID		09684	06622
Ensembl ID		ENSG00000052126	ENSG00000120509
Uniprot IDs		A0A024RAY7 Q9HAU0	Q5EBL8
PDB IDs		2DKP
Enriched GO Terms of Interacting Partners?
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