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PLD2 and GAPDH
Data Source:
HPRD
(in vivo, in vitro)
PLD2
GAPDH
Description
phospholipase D2
glyceraldehyde-3-phosphate dehydrogenase
Image
GO Annotations
Cellular Component
Endoplasmic Reticulum Membrane
Plasma Membrane
Presynapse
Nucleus
Cytoplasm
Lipid Droplet
Cytosol
Plasma Membrane
Microtubule Cytoskeleton
Membrane
Nuclear Membrane
Vesicle
Intracellular Membrane-bounded Organelle
Perinuclear Region Of Cytoplasm
Extracellular Exosome
GAIT Complex
Ribonucleoprotein Complex
Molecular Function
Phospholipase D Activity
Protein Binding
Phosphatidylinositol Binding
N-acylphosphatidylethanolamine-specific Phospholipase D Activity
Glyceraldehyde-3-phosphate Dehydrogenase (NAD+) (phosphorylating) Activity
Protein Binding
Microtubule Binding
Aspartic-type Endopeptidase Inhibitor Activity
Peptidyl-cysteine S-nitrosylase Activity
Identical Protein Binding
NADP Binding
NAD Binding
Disordered Domain Specific Binding
Biological Process
Phosphatidic Acid Biosynthetic Process
Cytoskeleton Organization
Small GTPase Mediated Signal Transduction
Lipid Catabolic Process
Synaptic Vesicle Recycling
Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis
Inositol Lipid-mediated Signaling
Cell Motility
Microtubule Cytoskeleton Organization
Positive Regulation Of Cytokine Production
Gluconeogenesis
Glycolytic Process
Negative Regulation Of Endopeptidase Activity
Regulation Of Macroautophagy
Negative Regulation Of Translation
Killing Of Cells Of Other Organism
Peptidyl-cysteine S-trans-nitrosylation
Protein Stabilization
Defense Response To Fungus
Neuron Apoptotic Process
Killing By Host Of Symbiont Cells
Canonical Glycolysis
Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide
Cellular Response To Interferon-gamma
Pathways
Synthesis of PG
Synthesis of PA
Role of phospholipids in phagocytosis
Glycolysis
Gluconeogenesis
Drugs
Choline
Choline salicylate
NADH
Adenosine-5-Diphosphoribose
Thionicotinamide-Adenine-Dinucleotide
4-(2-Aminoethyl)Benzenesulfonyl Fluoride
Xanthinol
Copper
Artenimol
Diseases
GWAS
Sphingolipid levels (
22359512
)
Systemic lupus erythematosus (
26502338
)
Blood protein levels (
30072576
)
Interacting Genes
29 interacting genes:
ACTB
ACTN1
ALDOA
ALDOC
AMPH
AQP3
ARF1
BIN1
CAV1
CSK
DPYSL2
EGFR
FYN
GAPDH
GM2A
HIF1A
LCK
MTDH
MTOR
OPRM1
PEA15
PIP5K1A
PLCG1
PRKCA
PRKCD
RPTOR
SRC
STXBP1
VHL
84 interacting genes:
ACD
ACTB
ACTC1
ANXA1
ANXA7
APP
AR
ARL15
ATN1
ATXN1
BID
BPGM
BTBD2
CAMK1
CAMK2B
CAMK4
CDKN1A
CDKN2A
CHP1
DUX4
DYNLL1
EGFR
ERBB2
FBXO7
FKBP6
GADD45A
GAS7
GOT2
GRIA2
GRM1
HES1
HNF4G
HSPB2
HTT
ITGB5
KARS1
KAT5
KCNE3
LAMA4
LAMTOR5
LIG4
LINC01554
MAPK1
MTNR1A
MYOC
NFYC
NR1H4
OSMR
OSTF1
PAFAH1B3
PCDHA4
PCNA
PDIA2
PGK1
PLD2
POT1
POU2F2
PPM1E
PRDX1
PRKCI
PRPF40A
PSEN1
PSMD11
PTPRF
RAB2A
RBM5
RPA2
RXFP4
S100A6
SERPINB9
SIAH1
SIRT1
SLC2A1
SLC2A4
SMN1
SNCA
SUMO4
TERF1
TINF2
TK1
TPPP
USP25
YWHAE
YWHAQ
Entrez ID
5338
2597
HPRD ID
03857
00713
Ensembl ID
ENSG00000129219
ENSG00000111640
Uniprot IDs
O14939
P04406
V9HVZ4
PDB IDs
6OHM
6OHO
6OHP
6OHQ
6OHS
1U8F
1ZNQ
2FEH
3GPD
4WNC
4WNI
6ADE
6IQ6
6YND
6YNE
6YNF
6YNH
Enriched GO Terms of Interacting Partners
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