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PLD2 and PEA15
Data Source:
HPRD
(in vivo)
PLD2
PEA15
Description
phospholipase D2
proliferation and apoptosis adaptor protein 15
Image
GO Annotations
Cellular Component
Endoplasmic Reticulum Membrane
Plasma Membrane
Presynapse
Nucleoplasm
Cytosol
Microtubule Associated Complex
Molecular Function
Phospholipase D Activity
Protein Binding
Phosphatidylinositol Binding
N-acylphosphatidylethanolamine-specific Phospholipase D Activity
Protein Binding
Biological Process
Phosphatidic Acid Biosynthetic Process
Cytoskeleton Organization
Small GTPase Mediated Signal Transduction
Lipid Catabolic Process
Synaptic Vesicle Recycling
Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis
Inositol Lipid-mediated Signaling
Cell Motility
MAPK Cascade
Activation Of MAPK Activity
Apoptotic Process
Carbohydrate Transport
Response To Morphine
Negative Regulation Of Glucose Import
Negative Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors
Positive Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors
Pathways
Synthesis of PG
Synthesis of PA
Role of phospholipids in phagocytosis
RAF-independent MAPK1/3 activation
RAF/MAP kinase cascade
Drugs
Choline
Choline salicylate
Diseases
GWAS
Sphingolipid levels (
22359512
)
Systemic lupus erythematosus (
26502338
)
Interacting Genes
29 interacting genes:
ACTB
ACTN1
ALDOA
ALDOC
AMPH
AQP3
ARF1
BIN1
CAV1
CSK
DPYSL2
EGFR
FYN
GAPDH
GM2A
HIF1A
LCK
MTDH
MTOR
OPRM1
PEA15
PIP5K1A
PLCG1
PRKCA
PRKCD
RPTOR
SRC
STXBP1
VHL
40 interacting genes:
ABCD4
AK9
AKT1
ATP1B3
CACYBP
CAMK2G
CASP8
CEP120
COPS5
DNAJB1
DYRK1A
FADD
HTRA2
KLHL12
L1CAM
LUC7L2
MAPK1
MAPK3
MTIF3
OSBPL1A
PANK4
PDE4DIP
PDPK1
PGM1
PLD1
PLD2
PPP4R3A
PRKCA
PUS3
RAMAC
RPS6KA3
RPSA
RSL24D1
SNRPG
SON
TALDO1
TENT4B
TERF2IP
TJP1
TRAPPC13
Entrez ID
5338
8682
HPRD ID
03857
04579
Ensembl ID
ENSG00000129219
ENSG00000162734
Uniprot IDs
O14939
B1AKZ4
B1AKZ5
Q15121
Q96FS5
PDB IDs
6OHM
6OHO
6OHP
6OHQ
6OHS
4IZ5
4IZA
6P6B
6P6C
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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