Wiki-MPM
About
Search
Browse
People
Funding
Updates
Search
GAPDH and YWHAE
Data Source:
BioGRID
(two hybrid)
GAPDH
YWHAE
Description
glyceraldehyde-3-phosphate dehydrogenase
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon
Image
GO Annotations
Cellular Component
Nucleus
Cytoplasm
Lipid Droplet
Cytosol
Plasma Membrane
Microtubule Cytoskeleton
Membrane
Nuclear Membrane
Vesicle
Intracellular Membrane-bounded Organelle
Perinuclear Region Of Cytoplasm
Extracellular Exosome
GAIT Complex
Ribonucleoprotein Complex
Nucleus
Cytoplasm
Mitochondrion
Cytosol
Kinesin Complex
Plasma Membrane
Focal Adhesion
Membrane
Melanosome
Extracellular Exosome
Central Region Of Growth Cone
Glutamatergic Synapse
Molecular Function
Glyceraldehyde-3-phosphate Dehydrogenase (NAD+) (phosphorylating) Activity
Protein Binding
Microtubule Binding
Aspartic-type Endopeptidase Inhibitor Activity
Peptidyl-cysteine S-nitrosylase Activity
Identical Protein Binding
NADP Binding
NAD Binding
Disordered Domain Specific Binding
RNA Binding
Calcium Channel Regulator Activity
Protein Binding
Potassium Channel Regulator Activity
Enzyme Binding
MHC Class II Protein Complex Binding
Ubiquitin Protein Ligase Binding
Identical Protein Binding
Histone Deacetylase Binding
Ion Channel Binding
Cadherin Binding
Protein Heterodimerization Activity
Phosphoserine Residue Binding
Phosphoprotein Binding
Scaffold Protein Binding
Biological Process
Microtubule Cytoskeleton Organization
Positive Regulation Of Cytokine Production
Gluconeogenesis
Glycolytic Process
Negative Regulation Of Endopeptidase Activity
Regulation Of Macroautophagy
Negative Regulation Of Translation
Killing Of Cells Of Other Organism
Peptidyl-cysteine S-trans-nitrosylation
Protein Stabilization
Defense Response To Fungus
Neuron Apoptotic Process
Killing By Host Of Symbiont Cells
Canonical Glycolysis
Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide
Cellular Response To Interferon-gamma
G2/M Transition Of Mitotic Cell Cycle
MAPK Cascade
Regulation Of Heart Rate By Hormone
Regulation Of G2/M Transition Of Mitotic Cell Cycle
Viral Process
Substantia Nigra Development
Protein Localization To Nucleus
Cellular Response To Heat
Hippo Signaling
Intracellular Signal Transduction
Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Positive Regulation Of Protein Export From Nucleus
Regulation Of Cytosolic Calcium Ion Concentration
Regulation Of Membrane Repolarization
Membrane Organization
Membrane Repolarization During Cardiac Muscle Cell Action Potential
Regulation Of Heart Rate By Cardiac Conduction
Ciliary Basal Body-plasma Membrane Docking
Regulation Of Postsynaptic Membrane Neurotransmitter Receptor Levels
Regulation Of Cellular Response To Heat
Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway
Regulation Of Potassium Ion Transmembrane Transporter Activity
Negative Regulation Of Calcium Ion Transmembrane Transporter Activity
Negative Regulation Of Peptidyl-serine Dephosphorylation
Negative Regulation Of Calcium Ion Export Across Plasma Membrane
Pathways
Glycolysis
Gluconeogenesis
Activation of BAD and translocation to mitochondria
Translocation of SLC2A4 (GLUT4) to the plasma membrane
Signaling by Hippo
NADE modulates death signalling
Regulation of PLK1 Activity at G2/M Transition
Regulation of HSF1-mediated heat shock response
HSF1 activation
Loss of Nlp from mitotic centrosomes
Recruitment of mitotic centrosome proteins and complexes
Loss of proteins required for interphase microtubule organization from the centrosome
Recruitment of NuMA to mitotic centrosomes
Anchoring of the basal body to the plasma membrane
RHO GTPases activate PKNs
TP53 Regulates Metabolic Genes
Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex
AURKA Activation by TPX2
Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models
RAB GEFs exchange GTP for GDP on RABs
Drugs
NADH
Adenosine-5-Diphosphoribose
Thionicotinamide-Adenine-Dinucleotide
4-(2-Aminoethyl)Benzenesulfonyl Fluoride
Xanthinol
Copper
Artenimol
Fusicoccin
Phenethyl Isothiocyanate
Diseases
Lissencephaly (LIS); Miller-Dieker syndrome (MDLS)
GWAS
Blood protein levels (
30072576
)
Atrial fibrillation (
30061737
)
High light scatter reticulocyte percentage of red cells (
32888494
)
Mean platelet volume (
32888494
)
Mean spheric corpuscular volume (
32888494
)
Nicotine dependence symptom count (
25555482
)
Reaction time (
29844566
)
Schizophrenia (
28991256
30285260
)
Interacting Genes
84 interacting genes:
ACD
ACTB
ACTC1
ANXA1
ANXA7
APP
AR
ARL15
ATN1
ATXN1
BID
BPGM
BTBD2
CAMK1
CAMK2B
CAMK4
CDKN1A
CDKN2A
CHP1
DUX4
DYNLL1
EGFR
ERBB2
FBXO7
FKBP6
GADD45A
GAS7
GOT2
GRIA2
GRM1
HES1
HNF4G
HSPB2
HTT
ITGB5
KARS1
KAT5
KCNE3
LAMA4
LAMTOR5
LIG4
LINC01554
MAPK1
MTNR1A
MYOC
NFYC
NR1H4
OSMR
OSTF1
PAFAH1B3
PCDHA4
PCNA
PDIA2
PGK1
PLD2
POT1
POU2F2
PPM1E
PRDX1
PRKCI
PRPF40A
PSEN1
PSMD11
PTPRF
RAB2A
RBM5
RPA2
RXFP4
S100A6
SERPINB9
SIAH1
SIRT1
SLC2A1
SLC2A4
SMN1
SNCA
SUMO4
TERF1
TINF2
TK1
TPPP
USP25
YWHAE
YWHAQ
147 interacting genes:
-
ABL1
ACD
AKAP13
AKAP9
ANKHD1-EIF4EBP3
ANKZF1
ARHGEF2
ARHGEF28
ATP6V0B
ATXN1
BAD
BCR
BEX3
CALM1
CAP2
CASK
CASP3
CCDC125
CCR9
CDC25A
CDC25B
CDK11B
CDK14
CDK16
CDKN1B
CEP131
CEP95
CGNL1
CHAF1A
CHST11
CYSLTR2
DDX54
DISC1
DYRK1A
ENKD1
EXO1
FAM13B
FAM53C
FGF12
FHL1
FTH1
GAPDH
GPRIN2
GRAP2
GSTA1
GSTM3
GTF2B
HDAC4
HDAC5
HIVEP2
HNRNPC
HSF1
HSPB1
IGF1R
IL7R
ING1
IRAG2
IRS1
IRS2
ITPRID2
KANK1
KCNH2
KCNK15
KCNK3
KCNK9
KIAA0232
KIF1C
KLC4
KRT18
LCP2
MAGEB4
MAP3K1
MAP3K10
MAP3K2
MAP3K3
MAP3K5
MAPK7
MCM10
MDM4
METAP2
MSL2
MST1R
MT-CO2
MYH10
NAF1
NCOR2
NDEL1
NIN
PAPOLA
PARD3B
PCM1
PIMREG
PNLIP
POT1
PRC1
PRDX6
PRKCG
RAB11FIP2
RAF1
RAP1GAP2
RASAL3
RASGRF1
RBIS
RBM14
REM1
RGS3
RIN1
RPA2
RPGR
RXFP3
SAMSN1
SH3BP4
SLC8A1
SLC8A2
SLC8A3
SMAGP
SNAPIN
SNCA
SNF8
SORBS2
SRC
SYN2
TAF7
TAZ
TBC1D3F
TBP
TCEANC
TFDP2
TGFB1
TLK1
TNFAIP3
TOP2A
TSC1
TSC2
UBE3A
USP43
VIM
WNK1
WWTR1
YWHAB
YWHAG
YWHAH
YWHAQ
YWHAZ
ZC3HC1
ZNF839
Entrez ID
2597
7531
HPRD ID
00713
05457
Ensembl ID
ENSG00000111640
ENSG00000108953
Uniprot IDs
P04406
V9HVZ4
P62258
V9HW98
PDB IDs
1U8F
1ZNQ
2FEH
3GPD
4WNC
4WNI
6ADE
6IQ6
6YND
6YNE
6YNF
6YNH
2BR9
3UAL
3UBW
6EIH
Enriched GO Terms of Interacting Partners
?
Tagcloud
?
Tagcloud (Difference)
?
Tagcloud (Intersection)
?