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GAPDH and TK1
Data Source:
BioGRID
(two hybrid)
HPRD
(two hybrid)
GAPDH
TK1
Description
glyceraldehyde-3-phosphate dehydrogenase
thymidine kinase 1
Image
GO Annotations
Cellular Component
Nucleus
Cytoplasm
Lipid Droplet
Cytosol
Plasma Membrane
Microtubule Cytoskeleton
Membrane
Nuclear Membrane
Vesicle
Intracellular Membrane-bounded Organelle
Perinuclear Region Of Cytoplasm
Extracellular Exosome
GAIT Complex
Ribonucleoprotein Complex
Cytosol
Molecular Function
Glyceraldehyde-3-phosphate Dehydrogenase (NAD+) (phosphorylating) Activity
Protein Binding
Microtubule Binding
Aspartic-type Endopeptidase Inhibitor Activity
Peptidyl-cysteine S-nitrosylase Activity
Identical Protein Binding
NADP Binding
NAD Binding
Disordered Domain Specific Binding
Thymidine Kinase Activity
Protein Binding
ATP Binding
Zinc Ion Binding
Identical Protein Binding
Biological Process
Microtubule Cytoskeleton Organization
Positive Regulation Of Cytokine Production
Gluconeogenesis
Glycolytic Process
Negative Regulation Of Endopeptidase Activity
Regulation Of Macroautophagy
Negative Regulation Of Translation
Killing Of Cells Of Other Organism
Peptidyl-cysteine S-trans-nitrosylation
Protein Stabilization
Defense Response To Fungus
Neuron Apoptotic Process
Killing By Host Of Symbiont Cells
Canonical Glycolysis
Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide
Cellular Response To Interferon-gamma
Nucleobase-containing Compound Metabolic Process
Deoxyribonucleoside Monophosphate Biosynthetic Process
Phosphorylation
Pyrimidine Nucleoside Salvage
Thymidine Metabolic Process
Protein Homotetramerization
DNA Biosynthetic Process
Pathways
Glycolysis
Gluconeogenesis
G1/S-Specific Transcription
Pyrimidine salvage
Drugs
NADH
Adenosine-5-Diphosphoribose
Thionicotinamide-Adenine-Dinucleotide
4-(2-Aminoethyl)Benzenesulfonyl Fluoride
Xanthinol
Copper
Artenimol
Dithioerythritol
Thymidine 5'-triphosphate
Diseases
GWAS
Blood protein levels (
30072576
)
Gut microbiota (bacterial taxa, hurdle binary method) (
32572223
)
Leukocyte telomere length (
32109421
)
Mean corpuscular hemoglobin (
32888494
27863252
)
Mean corpuscular volume (
32888494
27863252
)
Mean reticulocyte volume (
32888494
)
Mean spheric corpuscular volume (
32888494
)
Red cell distribution width (
32888494
27863252
28957414
)
Interacting Genes
84 interacting genes:
ACD
ACTB
ACTC1
ANXA1
ANXA7
APP
AR
ARL15
ATN1
ATXN1
BID
BPGM
BTBD2
CAMK1
CAMK2B
CAMK4
CDKN1A
CDKN2A
CHP1
DUX4
DYNLL1
EGFR
ERBB2
FBXO7
FKBP6
GADD45A
GAS7
GOT2
GRIA2
GRM1
HES1
HNF4G
HSPB2
HTT
ITGB5
KARS1
KAT5
KCNE3
LAMA4
LAMTOR5
LIG4
LINC01554
MAPK1
MTNR1A
MYOC
NFYC
NR1H4
OSMR
OSTF1
PAFAH1B3
PCDHA4
PCNA
PDIA2
PGK1
PLD2
POT1
POU2F2
PPM1E
PRDX1
PRKCI
PRPF40A
PSEN1
PSMD11
PTPRF
RAB2A
RBM5
RPA2
RXFP4
S100A6
SERPINB9
SIAH1
SIRT1
SLC2A1
SLC2A4
SMN1
SNCA
SUMO4
TERF1
TINF2
TK1
TPPP
USP25
YWHAE
YWHAQ
162 interacting genes:
A1BG
A2M
AAMP
ABHD4
ACTB
ACTL6B
ACTR1B
ADAMTS10
ADD1
AGAP1
ALAS1
ALB
APLP1
APP
ARFGAP1
ATG16L2
ATP5F1B
ATP6V1A
ATXN3
BAG6
BOLA2
BOLA2B
CARHSP1
CCDC115
CCDC90B
CDC20
CDK1
CDK4
CDKN1A
CENPB
CHGB
CLEC3B
COL11A2
COL4A2
COL4A5
COPS6
CPNE6
CRIP2
CRMP1
CSAD
DACT1
DALRD3
DCAF13
DDAH2
DEAF1
DMPK
DOCK7
DRAP1
DUS2
DYNC1I1
DYNC2I1
DYNLT2B
EEF1A1
EIF3G
EIF4A2
EIF6
ERG28
EXT2
EZH2
F13A1
FAF1
FAM20C
FBN3
FGB
FLAD1
FST
GAPDH
GDF9
GDI1
GET3
GLB1
GPCPD1
HADHB
HERC3
HMGXB3
HSPBAP1
IER3IP1
IGHM
IMMT
INPP5K
INTS11
ITSN1
JADE1
JMJD1C
KDM6B
KIF21B
KIF5A
KLHL23
KLHL5
KMT2B
LRIF1
MAGEA4
MAST2
MED31
METTL23
MKI67
MPP1
MPPED1
MRFAP1
MRPL20-AS1
MRPL37
MSH2
NEUROD2
NGFR
NKIRAS2
NMT2
NRBP1
ODC1
PAAF1
PDE4DIP
PJA1
PKM
PLD3
PLXNA3
PPP4C
PROC
PSME1
PTPN4
PTPRK
QARS1
RBBP4
RBM48
REX1BD
RPA1
RPL13
RPS2
RUVBL1
RXRA
SDF4
SEMA5B
SEPTIN6
SETDB1
SEZ6L2
SMC5
SNX1
SP110
SULT1A3
SUMO2
SUMO3
TAF1C
THOC3
TIAM2
TLE1
TMSB4X
TP53
TRIM46
TRMT2A
TSC2
TTC38
TUBA1A
TUBB2A
TUBB3
TYK2
UNC119
UPF2
USP4
WDR18
WDR73
WIZ
ZBTB16
ZNF431
ZXDC
Entrez ID
2597
7083
HPRD ID
00713
01771
Ensembl ID
ENSG00000111640
ENSG00000167900
Uniprot IDs
P04406
V9HVZ4
A0A384MDV9
K7ES52
P04183
PDB IDs
1U8F
1ZNQ
2FEH
3GPD
4WNC
4WNI
6ADE
6IQ6
6YND
6YNE
6YNF
6YNH
1W4R
1XBT
2ORV
2WVJ
Enriched GO Terms of Interacting Partners
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