GAPDH and OSMR

Data Source:
BioGRID (two hybrid)

		GAPDH	OSMR
Description		glyceraldehyde-3-phosphate dehydrogenase	oncostatin M receptor
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Lipid Droplet Cytosol Plasma Membrane Microtubule Cytoskeleton Membrane Nuclear Membrane Vesicle Intracellular Membrane-bounded Organelle Perinuclear Region Of Cytoplasm Extracellular Exosome GAIT Complex Ribonucleoprotein Complex	Plasma Membrane Oncostatin-M Receptor Complex External Side Of Plasma Membrane Apical Plasma Membrane Receptor Complex
	Molecular Function	Glyceraldehyde-3-phosphate Dehydrogenase (NAD+) (phosphorylating) Activity Protein Binding Microtubule Binding Aspartic-type Endopeptidase Inhibitor Activity Peptidyl-cysteine S-nitrosylase Activity Identical Protein Binding NADP Binding NAD Binding Disordered Domain Specific Binding	Cytokine Receptor Activity Leukemia Inhibitory Factor Receptor Activity Oncostatin-M Receptor Activity Ciliary Neurotrophic Factor Receptor Binding Protein Binding Growth Factor Binding Cytokine Binding
	Biological Process	Microtubule Cytoskeleton Organization Positive Regulation Of Cytokine Production Gluconeogenesis Glycolytic Process Negative Regulation Of Endopeptidase Activity Regulation Of Macroautophagy Negative Regulation Of Translation Killing Of Cells Of Other Organism Peptidyl-cysteine S-trans-nitrosylation Protein Stabilization Defense Response To Fungus Neuron Apoptotic Process Killing By Host Of Symbiont Cells Canonical Glycolysis Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Cellular Response To Interferon-gamma	Positive Regulation Of Acute Inflammatory Response Positive Regulation Of Cell Population Proliferation Cytokine-mediated Signaling Pathway Response To Cytokine Oncostatin-M-mediated Signaling Pathway Leukemia Inhibitory Factor Signaling Pathway
Pathways		Glycolysis Gluconeogenesis	IL-6-type cytokine receptor ligand interactions
Drugs		NADH Adenosine-5-Diphosphoribose Thionicotinamide-Adenine-Dinucleotide 4-(2-Aminoethyl)Benzenesulfonyl Fluoride Xanthinol Copper Artenimol
Diseases
GWAS		Blood protein levels ( 30072576)	Blood protein levels ( 29875488) Central retinal vein equivalent ( 31597446) Chronic inflammatory diseases (ankylosing spondylitis, Crohn's disease, psoriasis, primary sclerosing cholangitis, ulcerative colitis) (pleiotropy) ( 26974007) Crohn's disease ( 26192919 28067908) Daytime sleep phenotypes ( 27126917) Hematocrit ( 32888494) Hemoglobin ( 32888494) Hemoglobin levels ( 32327693) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Immature fraction of reticulocytes ( 32888494) Inflammatory bowel disease ( 26192919 28067908) Microalbuminuria ( 26631737) Night sleep phenotypes ( 27126917) Obesity-related traits ( 23251661) Postoperative survival time in hepatocellular carcinoma ( 30945673 30945699) Response to serotonin reuptake inhibitors in major depressive disorder ( 25897834) Reticulocyte fraction of red cells ( 32888494) Ulcerative colitis ( 26192919 28067908)
Interacting Genes		84 interacting genes: ACD ACTB ACTC1 ANXA1 ANXA7 APP AR ARL15 ATN1 ATXN1 BID BPGM BTBD2 CAMK1 CAMK2B CAMK4 CDKN1A CDKN2A CHP1 DUX4 DYNLL1 EGFR ERBB2 FBXO7 FKBP6 GADD45A GAS7 GOT2 GRIA2 GRM1 HES1 HNF4G HSPB2 HTT ITGB5 KARS1 KAT5 KCNE3 LAMA4 LAMTOR5 LIG4 LINC01554 MAPK1 MTNR1A MYOC NFYC NR1H4 OSMR OSTF1 PAFAH1B3 PCDHA4 PCNA PDIA2 PGK1 PLD2 POT1 POU2F2 PPM1E PRDX1 PRKCI PRPF40A PSEN1 PSMD11 PTPRF RAB2A RBM5 RPA2 RXFP4 S100A6 SERPINB9 SIAH1 SIRT1 SLC2A1 SLC2A4 SMN1 SNCA SUMO4 TERF1 TINF2 TK1 TPPP USP25 YWHAE YWHAQ	11 interacting genes: GAPDH GPRC5D IL6ST JAK1 JAK2 LHX2 MTDH OSM SGTB SLC10A6 UBQLN2
Entrez ID		2597	9180
HPRD ID		00713	03446
Ensembl ID		ENSG00000111640	ENSG00000145623
Uniprot IDs		P04406 V9HVZ4	Q99650
PDB IDs		1U8F 1ZNQ 2FEH 3GPD 4WNC 4WNI 6ADE 6IQ6 6YND 6YNE 6YNF 6YNH
Enriched GO Terms of Interacting Partners?
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