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TMX2 and TMBIM6
Data Source:
BioGRID
(two hybrid)
TMX2
TMBIM6
Description
thioredoxin related transmembrane protein 2
transmembrane BAX inhibitor motif containing 6
Image
No pdb structure
GO Annotations
Cellular Component
Mitochondrion
Endoplasmic Reticulum Membrane
Integral Component Of Membrane
Mitochondrial Membrane
Membrane-bounded Organelle
Mitochondria-associated Endoplasmic Reticulum Membrane
Nucleus
Cytoplasm
Endoplasmic Reticulum
Endoplasmic Reticulum Membrane
Integral Component Of Plasma Membrane
Membrane
Integral Component Of Membrane
Mitochondrial Membrane
Molecular Function
Protein Binding
Disulfide Oxidoreductase Activity
Identical Protein Binding
Protein Binding
Enzyme Binding
Ubiquitin Protein Ligase Binding
Endoribonuclease Inhibitor Activity
Biological Process
Brain Development
Negative Regulation Of Immunoglobulin Production
Autophagy
Negative Regulation Of Calcium Ion Transport Into Cytosol
Negative Regulation Of Protein Binding
Endoplasmic Reticulum Calcium Ion Homeostasis
Negative Regulation Of RNA Splicing
Cellular Response To Unfolded Protein
Negative Regulation Of Apoptotic Process
Negative Regulation Of Endoribonuclease Activity
Intrinsic Apoptotic Signaling Pathway In Response To Endoplasmic Reticulum Stress
Response To L-glutamate
Negative Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway
Negative Regulation Of Hypoxia-induced Intrinsic Apoptotic Signaling Pathway
Negative Regulation Of Transcription From RNA Polymerase II Promoter In Response To Endoplasmic Reticulum Stress
Negative Regulation Of Apoptotic Signaling Pathway
Pathways
Drugs
Diseases
GWAS
Autism spectrum disorder or schizophrenia (
28540026
)
Electrocardiogram morphology (amplitude at temporal datapoints) (
32916098
)
Neuroticism (
29255261
)
Problematic alcohol use (
32451486
)
Reticulocyte count (
32888494
)
Schizophrenia (
25056061
29483656
)
General cognitive ability (
29844566
)
Interacting Genes
164 interacting genes:
AGPAT3
AGPAT4
AGPAT5
AIG1
AQP6
ARV1
ASGR1
ASPH
ATXN1
BDKRB1
BET1
BNIP1
BNIP2
BNIP3
BRICD5
BTN2A2
C2CD2L
C3orf52
CCDC167
CCL2
CD81
CDIPT
CDS2
CMTM7
COL8A2
COMMD8
COX20
CTSA
CTXN3
CXCL16
CXorf66
CYBC1
CYP4F2
DERL1
DGAT2L6
EMD
EMP3
F2RL1
FA2H
FAM177A1
FAM241B
FAM3C
FAXDC2
FDFT1
FUNDC2
FXYD6-FXYD2
GIMAP1
GIMAP5
GJB2
HACD2
HHATL
HMOX2
HSD17B11
HSD17B13
HSD3B7
HTATIP2
IER3
IER3IP1
IGFBP5
INSIG2
ITGAM
LEPROT
LEPROTL1
LHFPL5
LRAT
MALL
MFF
MFSD14B
MGLL
MGST3
MIP
MLN
MS4A1
MTNR1A
NAT8
NDUFA3
NINJ2
NRM
NSDHL
NSG1
ORMDL2
OTULINL
PAEP
PEDS1-UBE2V1
PEX16
PKMYT1
PLP2
PNLIPRP1
PRAF2
PRB1
PTAFR
PTPN9
RABAC1
REEP2
REEP4
RFT1
RNF24
RTP2
RUSF1
SACM1L
SCAMP5
SCD
SELENOK
SERF1A
SERF1B
SERP2
SFT2D1
SFXN1
SFXN3
SLC22A18
SLC22A2
SLC29A2
SLC35A1
SMAGP
SMCO4
SMIM1
STATH
STX12
STX3
STX7
THBD
THSD7B
TMBIM6
TMEM115
TMEM120A
TMEM120B
TMEM121
TMEM128
TMEM140
TMEM14B
TMEM14C
TMEM176A
TMEM201
TMEM203
TMEM208
TMEM222
TMEM239
TMEM254
TMEM31
TMEM50B
TMEM51
TMEM65
TMEM71
TMEM86B
TMEM97
TPRG1
TRAM1L1
TREX1
TSNARE1
TSPAN2
TVP23B
UBE2J1
UNC93A
VAMP1
VAMP3
VAMP4
VAMP5
VAPA
VAPB
WFDC2
YIF1A
YIPF1
YIPF2
YIPF6
68 interacting genes:
ADIPOR2
ATP13A1
BCL2
BCL2L1
CD300LG
CD79A
CD99L2
CDC7
CERS2
CLDN22
COBLL1
CREB3L1
EBP
ENPP4
ERP29
ESAM
FAM209A
FERD3L
FGFBP2
FXYD3
GJA5
GJA8
GJB4
GLP1R
GPHB5
GPR151
GPR42
GPX8
GYPA
GZMK
HERPUD2
HJV
HTR2C
IER3
JSRP1
KCNA10
KCNC1
LIME1
LRRC59
MANBAL
MFSD14B
MMGT1
MS4A3
ODF4
OPRM1
PI16
PIANP
PVR
REEP2
RHBDL2
RNF185
SCN3B
SIT1
SLAMF6
SLC12A7
SLC41A3
SLC7A1
SOAT2
STEAP1B
SYT9
TEX29
TMEM31
TMUB1
TMX2
TNFRSF17
TREML1
UGT2B11
VTI1A
Entrez ID
51075
7009
HPRD ID
07159
02851
Ensembl ID
ENSG00000213593
ENSG00000139644
Uniprot IDs
Q9Y320
A0A024R0Z5
P55061
PDB IDs
2DJ0
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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