Wiki-MPM
About
Search
Browse
People
Funding
Updates
Search
TMX2 and CTSA
Data Source:
BioGRID
(two hybrid)
TMX2
CTSA
Description
thioredoxin related transmembrane protein 2
cathepsin A
Image
GO Annotations
Cellular Component
Mitochondrion
Endoplasmic Reticulum Membrane
Integral Component Of Membrane
Mitochondrial Membrane
Membrane-bounded Organelle
Mitochondria-associated Endoplasmic Reticulum Membrane
Extracellular Region
Lysosome
Endoplasmic Reticulum
Membrane
Azurophil Granule Lumen
Lysosomal Lumen
Intracellular Membrane-bounded Organelle
Extracellular Exosome
Lumenal Side Of Lysosomal Membrane
Molecular Function
Protein Binding
Disulfide Oxidoreductase Activity
Identical Protein Binding
Carboxypeptidase Activity
Serine-type Carboxypeptidase Activity
Enzyme Activator Activity
Biological Process
Brain Development
Proteolysis
Glycosphingolipid Metabolic Process
Intracellular Protein Transport
Regulation Of Protein Stability
Neutrophil Degranulation
Regulation Of Catalytic Activity
Regulation Of Chaperone-mediated Autophagy
Negative Regulation Of Chaperone-mediated Autophagy
Pathways
Glycosphingolipid metabolism
MHC class II antigen presentation
Sialic acid metabolism
Defective NEU1 causes sialidosis
Neutrophil degranulation
Drugs
Diseases
Galactosialidosis
GWAS
Autism spectrum disorder or schizophrenia (
28540026
)
Electrocardiogram morphology (amplitude at temporal datapoints) (
32916098
)
Neuroticism (
29255261
)
Problematic alcohol use (
32451486
)
Reticulocyte count (
32888494
)
Schizophrenia (
25056061
29483656
)
Interacting Genes
164 interacting genes:
AGPAT3
AGPAT4
AGPAT5
AIG1
AQP6
ARV1
ASGR1
ASPH
ATXN1
BDKRB1
BET1
BNIP1
BNIP2
BNIP3
BRICD5
BTN2A2
C2CD2L
C3orf52
CCDC167
CCL2
CD81
CDIPT
CDS2
CMTM7
COL8A2
COMMD8
COX20
CTSA
CTXN3
CXCL16
CXorf66
CYBC1
CYP4F2
DERL1
DGAT2L6
EMD
EMP3
F2RL1
FA2H
FAM177A1
FAM241B
FAM3C
FAXDC2
FDFT1
FUNDC2
FXYD6-FXYD2
GIMAP1
GIMAP5
GJB2
HACD2
HHATL
HMOX2
HSD17B11
HSD17B13
HSD3B7
HTATIP2
IER3
IER3IP1
IGFBP5
INSIG2
ITGAM
LEPROT
LEPROTL1
LHFPL5
LRAT
MALL
MFF
MFSD14B
MGLL
MGST3
MIP
MLN
MS4A1
MTNR1A
NAT8
NDUFA3
NINJ2
NRM
NSDHL
NSG1
ORMDL2
OTULINL
PAEP
PEDS1-UBE2V1
PEX16
PKMYT1
PLP2
PNLIPRP1
PRAF2
PRB1
PTAFR
PTPN9
RABAC1
REEP2
REEP4
RFT1
RNF24
RTP2
RUSF1
SACM1L
SCAMP5
SCD
SELENOK
SERF1A
SERF1B
SERP2
SFT2D1
SFXN1
SFXN3
SLC22A18
SLC22A2
SLC29A2
SLC35A1
SMAGP
SMCO4
SMIM1
STATH
STX12
STX3
STX7
THBD
THSD7B
TMBIM6
TMEM115
TMEM120A
TMEM120B
TMEM121
TMEM128
TMEM140
TMEM14B
TMEM14C
TMEM176A
TMEM201
TMEM203
TMEM208
TMEM222
TMEM239
TMEM254
TMEM31
TMEM50B
TMEM51
TMEM65
TMEM71
TMEM86B
TMEM97
TPRG1
TRAM1L1
TREX1
TSNARE1
TSPAN2
TVP23B
UBE2J1
UNC93A
VAMP1
VAMP3
VAMP4
VAMP5
VAPA
VAPB
WFDC2
YIF1A
YIPF1
YIPF2
YIPF6
45 interacting genes:
AHNAK2
AQP2
AQP6
ARL13B
ASPH
BSND
CD79A
COQ9
CPLX4
CREB3L1
CSPG5
ERGIC3
FAM209A
FKBP7
FNDC9
GLB1
GORAB
HIBADH
LAMP2
LMNA
LTB4R2
MFSD14B
MGST3
MUC1
MYG1
NEU1
PSCA
REEP4
RHBDD1
RNF122
SAR1A
SGMS2
SIGLEC12
SLC18A1
SLC30A2
SPN
SSMEM1
STX2
THAP4
TMEM139
TMEM154
TMEM237
TMEM31
TMEM35A
TMX2
Entrez ID
51075
5476
HPRD ID
07159
02020
Ensembl ID
ENSG00000213593
ENSG00000064601
Uniprot IDs
Q9Y320
B4E324
P10619
X6R5C5
X6R8A1
PDB IDs
2DJ0
1IVY
3BP4
3BP7
3BXN
4AZ0
4AZ3
4CI9
4CIA
4CIB
4MWS
4MWT
6WIA
Enriched GO Terms of Interacting Partners
?
Tagcloud
?
Tagcloud (Difference)
?
Tagcloud (Intersection)
?