Wiki-MPM
About
Search
Browse
People
Funding
Updates
Search
TMBIM6 and CERS2
Data Source:
BioGRID
(two hybrid)
TMBIM6
CERS2
Description
transmembrane BAX inhibitor motif containing 6
ceramide synthase 2
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Nucleus
Cytoplasm
Endoplasmic Reticulum
Endoplasmic Reticulum Membrane
Integral Component Of Plasma Membrane
Membrane
Integral Component Of Membrane
Mitochondrial Membrane
Endoplasmic Reticulum
Endoplasmic Reticulum Membrane
Membrane
Integral Component Of Membrane
Molecular Function
Protein Binding
Enzyme Binding
Ubiquitin Protein Ligase Binding
Endoribonuclease Inhibitor Activity
DNA Binding
Protein Binding
N-acyltransferase Activity
Sphingosine N-acyltransferase Activity
Biological Process
Negative Regulation Of Immunoglobulin Production
Autophagy
Negative Regulation Of Calcium Ion Transport Into Cytosol
Negative Regulation Of Protein Binding
Endoplasmic Reticulum Calcium Ion Homeostasis
Negative Regulation Of RNA Splicing
Cellular Response To Unfolded Protein
Negative Regulation Of Apoptotic Process
Negative Regulation Of Endoribonuclease Activity
Intrinsic Apoptotic Signaling Pathway In Response To Endoplasmic Reticulum Stress
Response To L-glutamate
Negative Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway
Negative Regulation Of Hypoxia-induced Intrinsic Apoptotic Signaling Pathway
Negative Regulation Of Transcription From RNA Polymerase II Promoter In Response To Endoplasmic Reticulum Stress
Negative Regulation Of Apoptotic Signaling Pathway
Sphingolipid Biosynthetic Process
Ceramide Biosynthetic Process
Negative Regulation Of Axon Regeneration
Negative Regulation Of Schwann Cell Migration
Negative Regulation Of Schwann Cell Proliferation Involved In Axon Regeneration
Pathways
Sphingolipid de novo biosynthesis
Drugs
Diseases
GWAS
General cognitive ability (
29844566
)
Apolipoprotein A1 levels (
32203549
)
Body mass index (
26426971
)
Estimated glomerular filtration rate (
31152163
31015462
)
Facial attractiveness (female raters) (
30946739
)
Glycated hemoglobin levels (
28898252
)
HDL cholesterol (
30275531
)
HDL cholesterol levels (
32203549
)
LDL cholesterol (
24097068
)
LDL cholesterol levels (
28334899
)
Reticulocyte fraction of red cells (
27863252
)
Rhegmatogenous retinal detachment (
23585552
)
Interacting Genes
68 interacting genes:
ADIPOR2
ATP13A1
BCL2
BCL2L1
CD300LG
CD79A
CD99L2
CDC7
CERS2
CLDN22
COBLL1
CREB3L1
EBP
ENPP4
ERP29
ESAM
FAM209A
FERD3L
FGFBP2
FXYD3
GJA5
GJA8
GJB4
GLP1R
GPHB5
GPR151
GPR42
GPX8
GYPA
GZMK
HERPUD2
HJV
HTR2C
IER3
JSRP1
KCNA10
KCNC1
LIME1
LRRC59
MANBAL
MFSD14B
MMGT1
MS4A3
ODF4
OPRM1
PI16
PIANP
PVR
REEP2
RHBDL2
RNF185
SCN3B
SIT1
SLAMF6
SLC12A7
SLC41A3
SLC7A1
SOAT2
STEAP1B
SYT9
TEX29
TMEM31
TMUB1
TMX2
TNFRSF17
TREML1
UGT2B11
VTI1A
12 interacting genes:
ASGR1
ASGR2
ATP6V0C
DRD2
HSP90AA1
IER3IP1
PEX6
SLC19A2
SLC22A1
SLC39A1
TMBIM6
YIF1A
Entrez ID
7009
29956
HPRD ID
02851
06080
Ensembl ID
ENSG00000139644
ENSG00000143418
Uniprot IDs
A0A024R0Z5
P55061
Q96G23
PDB IDs
Enriched GO Terms of Interacting Partners
?
Tagcloud
?
Tagcloud (Difference)
?
Tagcloud (Intersection)
?