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TMBIM6 and RNF185
Data Source:
BioGRID
(two hybrid)
TMBIM6
RNF185
Description
transmembrane BAX inhibitor motif containing 6
ring finger protein 185
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Nucleus
Cytoplasm
Endoplasmic Reticulum
Endoplasmic Reticulum Membrane
Integral Component Of Plasma Membrane
Membrane
Integral Component Of Membrane
Mitochondrial Membrane
Mitochondrial Outer Membrane
Endoplasmic Reticulum
Endoplasmic Reticulum Membrane
Integral Component Of Membrane
Endoplasmic Reticulum Quality Control Compartment
Molecular Function
Protein Binding
Enzyme Binding
Ubiquitin Protein Ligase Binding
Endoribonuclease Inhibitor Activity
Protein Binding
Ubiquitin Binding
Ubiquitin-like Protein Conjugating Enzyme Binding
Protein-containing Complex Binding
Metal Ion Binding
Ubiquitin Protein Ligase Activity
Biological Process
Negative Regulation Of Immunoglobulin Production
Autophagy
Negative Regulation Of Calcium Ion Transport Into Cytosol
Negative Regulation Of Protein Binding
Endoplasmic Reticulum Calcium Ion Homeostasis
Negative Regulation Of RNA Splicing
Cellular Response To Unfolded Protein
Negative Regulation Of Apoptotic Process
Negative Regulation Of Endoribonuclease Activity
Intrinsic Apoptotic Signaling Pathway In Response To Endoplasmic Reticulum Stress
Response To L-glutamate
Negative Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway
Negative Regulation Of Hypoxia-induced Intrinsic Apoptotic Signaling Pathway
Negative Regulation Of Transcription From RNA Polymerase II Promoter In Response To Endoplasmic Reticulum Stress
Negative Regulation Of Apoptotic Signaling Pathway
Ubiquitin-dependent Protein Catabolic Process
Autophagy
Ubiquitin-dependent ERAD Pathway
ERAD Pathway
Protein Autoubiquitination
Transmembrane Transport
ER-associated Misfolded Protein Catabolic Process
Positive Regulation Of ERAD Pathway
Endoplasmic Reticulum Mannose Trimming
Pathways
ABC-family proteins mediated transport
Defective CFTR causes cystic fibrosis
ER Quality Control Compartment (ERQC)
Drugs
Diseases
GWAS
General cognitive ability (
29844566
)
Apolipoprotein A1 levels (
32203549
)
Fish- and plant-related diet (
32066663
)
Oily fish consumption (
32066663
)
Pork consumption (
32066663
)
Waist circumference (
28552196
)
White blood cell count (
32888494
)
Interacting Genes
68 interacting genes:
ADIPOR2
ATP13A1
BCL2
BCL2L1
CD300LG
CD79A
CD99L2
CDC7
CERS2
CLDN22
COBLL1
CREB3L1
EBP
ENPP4
ERP29
ESAM
FAM209A
FERD3L
FGFBP2
FXYD3
GJA5
GJA8
GJB4
GLP1R
GPHB5
GPR151
GPR42
GPX8
GYPA
GZMK
HERPUD2
HJV
HTR2C
IER3
JSRP1
KCNA10
KCNC1
LIME1
LRRC59
MANBAL
MFSD14B
MMGT1
MS4A3
ODF4
OPRM1
PI16
PIANP
PVR
REEP2
RHBDL2
RNF185
SCN3B
SIT1
SLAMF6
SLC12A7
SLC41A3
SLC7A1
SOAT2
STEAP1B
SYT9
TEX29
TMEM31
TMUB1
TMX2
TNFRSF17
TREML1
UGT2B11
VTI1A
32 interacting genes:
APP
CGAS
CMTM5
CYB561A3
DVL2
FAM241B
MALL
MS4A13
MTNR1B
MYADML2
NIPAL4
RNF5
TMBIM6
TMEM147
TMEM19
TMEM86A
UBE2D1
UBE2D2
UBE2D3
UBE2D4
UBE2E1
UBE2E2
UBE2E3
UBE2H
UBE2I
UBE2K
UBE2V1
UBE2W
USP21
YIPF2
YIPF4
YIPF6
Entrez ID
7009
91445
HPRD ID
02851
08790
Ensembl ID
ENSG00000139644
ENSG00000138942
Uniprot IDs
A0A024R0Z5
P55061
A0A024R1F5
A0A024R1H4
Q96GF1
PDB IDs
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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