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TMX2 and MIP
Data Source:
BioGRID
(two hybrid)
TMX2
MIP
Description
thioredoxin related transmembrane protein 2
major intrinsic protein of lens fiber
Image
No pdb structure
GO Annotations
Cellular Component
Mitochondrion
Endoplasmic Reticulum Membrane
Integral Component Of Membrane
Mitochondrial Membrane
Membrane-bounded Organelle
Mitochondria-associated Endoplasmic Reticulum Membrane
Endoplasmic Reticulum
Plasma Membrane
Integral Component Of Plasma Membrane
Gap Junction
Integral Component Of Membrane
Apical Plasma Membrane
Molecular Function
Protein Binding
Disulfide Oxidoreductase Activity
Identical Protein Binding
Structural Constituent Of Eye Lens
Protein Binding
Calmodulin Binding
Water Channel Activity
Biological Process
Brain Development
Lens Development In Camera-type Eye
Water Transport
Visual Perception
Positive Regulation Of Cell Adhesion
Response To Stimulus
Protein Homotetramerization
Transmembrane Transport
Gap Junction-mediated Intercellular Transport
Pathways
Passive transport by Aquaporins
Drugs
B-nonylglucoside
Diseases
GWAS
Autism spectrum disorder or schizophrenia (
28540026
)
Electrocardiogram morphology (amplitude at temporal datapoints) (
32916098
)
Neuroticism (
29255261
)
Problematic alcohol use (
32451486
)
Reticulocyte count (
32888494
)
Schizophrenia (
25056061
29483656
)
Axial length (
24144296
)
Interacting Genes
164 interacting genes:
AGPAT3
AGPAT4
AGPAT5
AIG1
AQP6
ARV1
ASGR1
ASPH
ATXN1
BDKRB1
BET1
BNIP1
BNIP2
BNIP3
BRICD5
BTN2A2
C2CD2L
C3orf52
CCDC167
CCL2
CD81
CDIPT
CDS2
CMTM7
COL8A2
COMMD8
COX20
CTSA
CTXN3
CXCL16
CXorf66
CYBC1
CYP4F2
DERL1
DGAT2L6
EMD
EMP3
F2RL1
FA2H
FAM177A1
FAM241B
FAM3C
FAXDC2
FDFT1
FUNDC2
FXYD6-FXYD2
GIMAP1
GIMAP5
GJB2
HACD2
HHATL
HMOX2
HSD17B11
HSD17B13
HSD3B7
HTATIP2
IER3
IER3IP1
IGFBP5
INSIG2
ITGAM
LEPROT
LEPROTL1
LHFPL5
LRAT
MALL
MFF
MFSD14B
MGLL
MGST3
MIP
MLN
MS4A1
MTNR1A
NAT8
NDUFA3
NINJ2
NRM
NSDHL
NSG1
ORMDL2
OTULINL
PAEP
PEDS1-UBE2V1
PEX16
PKMYT1
PLP2
PNLIPRP1
PRAF2
PRB1
PTAFR
PTPN9
RABAC1
REEP2
REEP4
RFT1
RNF24
RTP2
RUSF1
SACM1L
SCAMP5
SCD
SELENOK
SERF1A
SERF1B
SERP2
SFT2D1
SFXN1
SFXN3
SLC22A18
SLC22A2
SLC29A2
SLC35A1
SMAGP
SMCO4
SMIM1
STATH
STX12
STX3
STX7
THBD
THSD7B
TMBIM6
TMEM115
TMEM120A
TMEM120B
TMEM121
TMEM128
TMEM140
TMEM14B
TMEM14C
TMEM176A
TMEM201
TMEM203
TMEM208
TMEM222
TMEM239
TMEM254
TMEM31
TMEM50B
TMEM51
TMEM65
TMEM71
TMEM86B
TMEM97
TPRG1
TRAM1L1
TREX1
TSNARE1
TSPAN2
TVP23B
UBE2J1
UNC93A
VAMP1
VAMP3
VAMP4
VAMP5
VAPA
VAPB
WFDC2
YIF1A
YIPF1
YIPF2
YIPF6
47 interacting genes:
AQP9
ATP6V0B
CALM1
CD40
CISD2
CLDN5
CRYAA
CRYAB
CRYBB2
CRYGC
ERGIC3
ERVFRD-1
FAM209A
FCGR2A
FOXA2
GJA3
GJA8
GJB5
GOLM1
GPX8
KCNJ6
LHFPL5
LMNA
LRRC4C
MFF
MGST3
MRM3
MRPS18B
MUC1
PDZK1IP1
PRKACA
RELL2
SAR1A
SGPL1
SLC14A1
SLC18A1
SSMEM1
STX1A
STX2
SYAP1
SYT1
SYT2
TMEM139
TMEM154
TMEM52B
TMX2
ZFPL1
Entrez ID
51075
4284
HPRD ID
07159
01098
Ensembl ID
ENSG00000213593
ENSG00000135517
Uniprot IDs
Q9Y320
P30301
PDB IDs
2DJ0
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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