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TMBIM6 and ESAM
Data Source:
BioGRID
(two hybrid)
TMBIM6
ESAM
Description
transmembrane BAX inhibitor motif containing 6
endothelial cell adhesion molecule
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Nucleus
Cytoplasm
Endoplasmic Reticulum
Endoplasmic Reticulum Membrane
Integral Component Of Plasma Membrane
Membrane
Integral Component Of Membrane
Mitochondrial Membrane
Plasma Membrane
Cell-cell Junction
Adherens Junction
Bicellular Tight Junction
Integral Component Of Membrane
Protein-containing Complex
Molecular Function
Protein Binding
Enzyme Binding
Ubiquitin Protein Ligase Binding
Endoribonuclease Inhibitor Activity
Protein Binding
Cell-cell Adhesion Mediator Activity
Biological Process
Negative Regulation Of Immunoglobulin Production
Autophagy
Negative Regulation Of Calcium Ion Transport Into Cytosol
Negative Regulation Of Protein Binding
Endoplasmic Reticulum Calcium Ion Homeostasis
Negative Regulation Of RNA Splicing
Cellular Response To Unfolded Protein
Negative Regulation Of Apoptotic Process
Negative Regulation Of Endoribonuclease Activity
Intrinsic Apoptotic Signaling Pathway In Response To Endoplasmic Reticulum Stress
Response To L-glutamate
Negative Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway
Negative Regulation Of Hypoxia-induced Intrinsic Apoptotic Signaling Pathway
Negative Regulation Of Transcription From RNA Polymerase II Promoter In Response To Endoplasmic Reticulum Stress
Negative Regulation Of Apoptotic Signaling Pathway
Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules
Regulation Of Actin Filament Polymerization
Cellular Protein Localization
Maintenance Of Blood-brain Barrier
Leukocyte Migration
Bicellular Tight Junction Assembly
Cell-cell Adhesion
Regulation Of Actin Cytoskeleton Reorganization
Pathways
Cell surface interactions at the vascular wall
Drugs
Diseases
GWAS
General cognitive ability (
29844566
)
Autism spectrum disorder or schizophrenia (
28540026
)
Blood protein levels (
30072576
29875488
28240269
)
Schizophrenia (
25056061
29483656
)
Interacting Genes
68 interacting genes:
ADIPOR2
ATP13A1
BCL2
BCL2L1
CD300LG
CD79A
CD99L2
CDC7
CERS2
CLDN22
COBLL1
CREB3L1
EBP
ENPP4
ERP29
ESAM
FAM209A
FERD3L
FGFBP2
FXYD3
GJA5
GJA8
GJB4
GLP1R
GPHB5
GPR151
GPR42
GPX8
GYPA
GZMK
HERPUD2
HJV
HTR2C
IER3
JSRP1
KCNA10
KCNC1
LIME1
LRRC59
MANBAL
MFSD14B
MMGT1
MS4A3
ODF4
OPRM1
PI16
PIANP
PVR
REEP2
RHBDL2
RNF185
SCN3B
SIT1
SLAMF6
SLC12A7
SLC41A3
SLC7A1
SOAT2
STEAP1B
SYT9
TEX29
TMEM31
TMUB1
TMX2
TNFRSF17
TREML1
UGT2B11
VTI1A
3 interacting genes:
C3orf52
MTDH
TMBIM6
Entrez ID
7009
90952
HPRD ID
02851
13280
Ensembl ID
ENSG00000139644
ENSG00000149564
Uniprot IDs
A0A024R0Z5
P55061
Q96AP7
PDB IDs
Enriched GO Terms of Interacting Partners
?
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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