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TMBIM6 and HJV
Data Source:
BioGRID
(two hybrid)
TMBIM6
HJV
Description
transmembrane BAX inhibitor motif containing 6
hemojuvelin BMP co-receptor
Image
No pdb structure
GO Annotations
Cellular Component
Nucleus
Cytoplasm
Endoplasmic Reticulum
Endoplasmic Reticulum Membrane
Integral Component Of Plasma Membrane
Membrane
Integral Component Of Membrane
Mitochondrial Membrane
Extracellular Space
Plasma Membrane
Anchored Component Of Membrane
BMP Receptor Complex
Plasma Membrane Protein Complex
HFE-transferrin Receptor Complex
Molecular Function
Protein Binding
Enzyme Binding
Ubiquitin Protein Ligase Binding
Endoribonuclease Inhibitor Activity
Signaling Receptor Binding
Protein Binding
Coreceptor Activity
BMP Binding
BMP Receptor Activity
Transferrin Receptor Binding
Biological Process
Negative Regulation Of Immunoglobulin Production
Autophagy
Negative Regulation Of Calcium Ion Transport Into Cytosol
Negative Regulation Of Protein Binding
Endoplasmic Reticulum Calcium Ion Homeostasis
Negative Regulation Of RNA Splicing
Cellular Response To Unfolded Protein
Negative Regulation Of Apoptotic Process
Negative Regulation Of Endoribonuclease Activity
Intrinsic Apoptotic Signaling Pathway In Response To Endoplasmic Reticulum Stress
Response To L-glutamate
Negative Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway
Negative Regulation Of Hypoxia-induced Intrinsic Apoptotic Signaling Pathway
Negative Regulation Of Transcription From RNA Polymerase II Promoter In Response To Endoplasmic Reticulum Stress
Negative Regulation Of Apoptotic Signaling Pathway
Negative Regulation Of Transcription By RNA Polymerase II
Cellular Iron Ion Homeostasis
Protein Autoprocessing
BMP Signaling Pathway
Activin Receptor Signaling Pathway
Positive Regulation Of Transcription By RNA Polymerase II
Iron Ion Homeostasis
Cellular Response To BMP Stimulus
Pathways
Netrin-1 signaling
Drugs
Diseases
Hemochromatosis (HFE); Juvenile hemochromatosis (JH)
GWAS
General cognitive ability (
29844566
)
Interacting Genes
68 interacting genes:
ADIPOR2
ATP13A1
BCL2
BCL2L1
CD300LG
CD79A
CD99L2
CDC7
CERS2
CLDN22
COBLL1
CREB3L1
EBP
ENPP4
ERP29
ESAM
FAM209A
FERD3L
FGFBP2
FXYD3
GJA5
GJA8
GJB4
GLP1R
GPHB5
GPR151
GPR42
GPX8
GYPA
GZMK
HERPUD2
HJV
HTR2C
IER3
JSRP1
KCNA10
KCNC1
LIME1
LRRC59
MANBAL
MFSD14B
MMGT1
MS4A3
ODF4
OPRM1
PI16
PIANP
PVR
REEP2
RHBDL2
RNF185
SCN3B
SIT1
SLAMF6
SLC12A7
SLC41A3
SLC7A1
SOAT2
STEAP1B
SYT9
TEX29
TMEM31
TMUB1
TMX2
TNFRSF17
TREML1
UGT2B11
VTI1A
1 interacting genes:
TMBIM6
Entrez ID
7009
148738
HPRD ID
02851
10521
Ensembl ID
ENSG00000139644
ENSG00000168509
Uniprot IDs
A0A024R0Z5
P55061
A0A024R4F5
A8K466
Q6ZVN8
PDB IDs
4UI1
6Z3L
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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