PIGP and C1GALT1

Data Source:
BioGRID (two hybrid)

		PIGP	C1GALT1
Description		phosphatidylinositol glycan anchor biosynthesis class P	core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) Complex Endoplasmic Reticulum Membrane Integral Component Of Membrane	Golgi Membrane Integral Component Of Membrane
	Molecular Function	Protein Binding Phosphatidylinositol N-acetylglucosaminyltransferase Activity	Protein Binding Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase Activity Metal Ion Binding
	Biological Process	GPI Anchor Biosynthetic Process Preassembly Of GPI Anchor In ER Membrane	Angiogenesis Kidney Development O-glycan Processing O-glycan Processing, Core 1 Protein Phosphopantetheinylation Cell Differentiation
Pathways		Synthesis of glycosylphosphatidylinositol (GPI)	Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS) O-linked glycosylation of mucins
Drugs
Diseases
GWAS			Blood protein levels ( 29875488) Chronic obstructive pulmonary disease or high blood pressure (pleiotropy) ( 30940143) Coronary artery disease ( 29212778) Daytime sleep phenotypes ( 27126917) Diastolic blood pressure ( 30224653) Erosive tooth wear (severe vs non-severe) ( 29898447) FEV1 ( 30804560) Lung function (FEV1/FVC) ( 28166213 30804560) Medication use (agents acting on the renin-angiotensin system) ( 31015401) Multiple sclerosis (severity) ( 19010793) Night sleep phenotypes ( 27126917) Peak expiratory flow ( 30804560) Refractive error ( 32231278) Serum galactose-deficient IgA1 levels ( 28187132) Smooth-surface caries ( 24556642) Systolic blood pressure ( 26969751) Visceral adipose tissue adjusted for BMI ( 22589738)
Interacting Genes		17 interacting genes: C1GALT1 DHRSX FIS1 IER3IP1 ITGAM LHFPL3 NINJ2 PLP1 PLP2 PTPN1 SCAMP5 SMAGP THSD7B TMEM107 TMEM19 TMEM229B UBIAD1	30 interacting genes: ANKS6 ARL13B C1GALT1C1 CD79A CPLX4 ELOVL4 FAM209A FAM210B GJA8 GJB1 GJB5 GPR101 GPR151 GPR42 GPRC5D GPX8 LEPROT LEUTX LHFPL5 MUC1 PIGP RETREG3 SLC14A1 SLC1A1 SLC7A14 STX1A TMEM14B TMEM237 TMEM52B XRN1
Entrez ID		51227	56913
HPRD ID		05806	16631
Ensembl ID		ENSG00000185808	ENSG00000106392
Uniprot IDs		P57054	A0A024RA32 Q9NS00
PDB IDs
Enriched GO Terms of Interacting Partners?
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