NDUFB7 and MLKL

Data Source:
BioGRID (two hybrid)

		NDUFB7	MLKL
Description		NADH:ubiquinone oxidoreductase subunit B7	mixed lineage kinase domain like pseudokinase
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GO Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane Mitochondrial Respiratory Chain Complex I Mitochondrial Intermembrane Space	Nucleus Cytoplasm Cytosol Plasma Membrane Cell Junction
	Molecular Function	Protein Binding NADH Dehydrogenase (ubiquinone) Activity	Protein Kinase Activity JUN Kinase Kinase Kinase Activity Protein Binding ATP Binding Protein Kinase Binding Protein-containing Complex Binding
	Biological Process	Mitochondrial Electron Transport, NADH To Ubiquinone Mitochondrial Respiratory Chain Complex I Assembly	Protein Phosphorylation Cell Surface Receptor Signaling Pathway Activation Of JNKK Activity Activation Of JUN Kinase Activity Defense Response To Virus Protein Homotrimerization Necroptotic Process Necroptotic Signaling Pathway Execution Phase Of Necroptosis
Pathways		Respiratory electron transport Complex I biogenesis	TRP channels RIPK1-mediated regulated necrosis Regulation of necroptotic cell death Microbial modulation of RIPK1-mediated regulated necrosis
Drugs		NADH
Diseases
GWAS			Testicular germ cell tumor ( 23666239)
Interacting Genes		41 interacting genes: AGBL2 ANKRD36B ATG9A C1orf109 CAPN1 CCDC24 CCNC CDCA7L CDKN2D CHIC2 CINP CKAP4 CTNNA3 ENKD1 FAM161B FAM90A1 GEM GPATCH2L GYS1 KRTAP10-10 LMO2 MAGOHB MAK MEIS2 MKRN3 MLKL NDUFB2 NFKBIB NFKBID RCOR3 RECK RIPPLY1 RIPPLY2 SCNM1 SPRED2 STRA6 TLE5 ZNF330 ZNF417 ZNF564 ZNF587	7 interacting genes: ANAPC11 CDK1 NDUFB7 PSMB1 RAD18 S100A10 THOC3
Entrez ID		4713	197259
HPRD ID		11957	08752
Ensembl ID		ENSG00000099795	ENSG00000168404
Uniprot IDs		P17568	Q8NB16
PDB IDs		5XTC 5XTD 5XTH 5XTI	2MSV 4M67 4MWI 5KNJ 5KO1 6BWK 6D74 6O5Z 6UX8
Enriched GO Terms of Interacting Partners?
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