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MGST3 and MIP
Data Source:
BioGRID
(two hybrid)
MGST3
MIP
Description
microsomal glutathione S-transferase 3
major intrinsic protein of lens fiber
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Nuclear Envelope
Endoplasmic Reticulum
Endoplasmic Reticulum Membrane
Membrane
Integral Component Of Membrane
Intracellular Membrane-bounded Organelle
Endoplasmic Reticulum
Plasma Membrane
Integral Component Of Plasma Membrane
Gap Junction
Integral Component Of Membrane
Apical Plasma Membrane
Molecular Function
Glutathione Transferase Activity
Leukotriene-C4 Synthase Activity
Glutathione Peroxidase Activity
Protein Binding
Identical Protein Binding
Structural Constituent Of Eye Lens
Protein Binding
Calmodulin Binding
Water Channel Activity
Biological Process
Lipid Metabolic Process
Xenobiotic Metabolic Process
Leukotriene Biosynthetic Process
Cellular Oxidant Detoxification
Glutathione Derivative Biosynthetic Process
Lens Development In Camera-type Eye
Water Transport
Visual Perception
Positive Regulation Of Cell Adhesion
Response To Stimulus
Protein Homotetramerization
Transmembrane Transport
Gap Junction-mediated Intercellular Transport
Pathways
Glutathione conjugation
Aflatoxin activation and detoxification
Passive transport by Aquaporins
Drugs
Glutathione
B-nonylglucoside
Diseases
GWAS
Metabolite levels (
23823483
)
Total ventricular volume (
21116278
)
Axial length (
24144296
)
Interacting Genes
86 interacting genes:
AGPAT4
AGTRAP
APOD
APOL2
AQP1
AQP10
AQP3
ARL6IP1
ARL6IP6
BET1
BMP10
C11orf24
C14orf180
C3orf52
CACNG1
CCNC
CDIPT
CLCA4
CLRN1
CMTM5
CREB3L1
CTSA
CYBC1
ERG28
F10
FAXDC2
FUNDC2
FXYD6
GIMAP1
GIMAP5
GPR152
GPX8
GRM2
HMOX2
ITGAM
LEMD1
LMNA
LPAR3
LRP10
MIP
MRM1
MTIF3
NEU1
NINJ2
NKG7
NRM
NSG1
PAGE1
PLN
PLP1
PLP2
PLPP4
SCD
SCN3B
SEC22B
SLC1A3
SLC2A5
SLC35A1
SLC39A9
SLC7A1
SMCO4
SNAP47
SNORC
STX3
STX7
STX8
SYS1
TFAM
TFRC
TMEM107
TMEM109
TMEM120B
TMEM140
TMEM229B
TMEM60
TMEM86B
TMX2
TSPAN12
TSPAN2
TSPAN33
UBIAD1
UNC50
VAMP3
VAMP4
YIF1A
ZFPL1
47 interacting genes:
AQP9
ATP6V0B
CALM1
CD40
CISD2
CLDN5
CRYAA
CRYAB
CRYBB2
CRYGC
ERGIC3
ERVFRD-1
FAM209A
FCGR2A
FOXA2
GJA3
GJA8
GJB5
GOLM1
GPX8
KCNJ6
LHFPL5
LMNA
LRRC4C
MFF
MGST3
MRM3
MRPS18B
MUC1
PDZK1IP1
PRKACA
RELL2
SAR1A
SGPL1
SLC14A1
SLC18A1
SSMEM1
STX1A
STX2
SYAP1
SYT1
SYT2
TMEM139
TMEM154
TMEM52B
TMX2
ZFPL1
Entrez ID
4259
4284
HPRD ID
05192
01098
Ensembl ID
ENSG00000143198
ENSG00000135517
Uniprot IDs
A0A024R8Z1
O14880
P30301
PDB IDs
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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