MIP and CRYBB2

Data Source:
BioGRID (fluorescent resonance energy transfer)

		MIP	CRYBB2
Description		major intrinsic protein of lens fiber	crystallin beta B2
Image		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Plasma Membrane Integral Component Of Plasma Membrane Gap Junction Integral Component Of Membrane Apical Plasma Membrane
	Molecular Function	Structural Constituent Of Eye Lens Protein Binding Calmodulin Binding Water Channel Activity	Structural Molecule Activity Structural Constituent Of Eye Lens Protein Binding Identical Protein Binding
	Biological Process	Lens Development In Camera-type Eye Water Transport Visual Perception Positive Regulation Of Cell Adhesion Response To Stimulus Protein Homotetramerization Transmembrane Transport Gap Junction-mediated Intercellular Transport	Lens Development In Camera-type Eye Visual Perception Response To Stimulus
Pathways		Passive transport by Aquaporins
Drugs		B-nonylglucoside
Diseases
GWAS		Axial length ( 24144296)	Adverse response to drug ( 30420678)
Interacting Genes		47 interacting genes: AQP9 ATP6V0B CALM1 CD40 CISD2 CLDN5 CRYAA CRYAB CRYBB2 CRYGC ERGIC3 ERVFRD-1 FAM209A FCGR2A FOXA2 GJA3 GJA8 GJB5 GOLM1 GPX8 KCNJ6 LHFPL5 LMNA LRRC4C MFF MGST3 MRM3 MRPS18B MUC1 PDZK1IP1 PRKACA RELL2 SAR1A SGPL1 SLC14A1 SLC18A1 SSMEM1 STX1A STX2 SYAP1 SYT1 SYT2 TMEM139 TMEM154 TMEM52B TMX2 ZFPL1	9 interacting genes: CRYAA CRYAB CRYBA1 CRYBA2 CRYBA4 CRYGC HSPB1 LMO4 MIP
Entrez ID		4284	1415
HPRD ID		01098	00430
Ensembl ID		ENSG00000135517	ENSG00000244752
Uniprot IDs		P30301	P43320 R4UMM2
PDB IDs			1YTQ
Enriched GO Terms of Interacting Partners?
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